Search for dissertations about: "airway remodeling"

Showing result 6 - 10 of 19 swedish dissertations containing the words airway remodeling.

  2. 6. On dysregulated inflammation and airway host defense

    Author : Ravi K. V. Bhongir; allergologi och palliativ medicin Lungmedicin; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aiway inflammation; Chronic obstructive pulmonary disease COPD ; Cystic Fibrosis; Pseudomonas aeruginosa; DNase I;

    Abstract : Acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and cystic fibrosis (CF) are characterized by dysregulated inflammation of the airways. The increased influx of immune cells and the accumulation of cytokines lead to cell death, tissue destruction and impaired pulmonary function. READ MORE

  4. 7. On airway host defence during allergic inflammation

    Author : Anele Gela; allergologi och palliativ medicin Lungmedicin; []
    Keywords : Asthma; COPD; Antimicrobial peptide; chemokines; immunology;

    Abstract : Asthma is a chronic inflammatory disease of the airways, affecting and disablingapproximately 300 million people worldwide. The inflammatory profile ischaracterized by infiltration of eosinophils, which are a rich source of factors thatare implicated in tissue remodeling. READ MORE

  5. 8. Early airway inflammation in allergic asthma : aspects of pulmonary innate immunity

    Author : Catarina Lensmar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : allergic asthma; low-dose allergen challenge; induced sputum; alveolar macrophage; cytokine; CC16; antibacterial activity; antibacterial peptide;

    Abstract : Allergic asthma is a chronic disease in which allergen-induced inflammatory processes of the airways contribute to the development of symptoms and eventually may lead to remodeling of the airway tissue. In the present work low-dose allergen inhalation challenges of individuals with asthma were used as a model to delineate inflammatory events occurring in an early phase of the allergic airway inflammation associated with asthma. READ MORE

  6. 9. Mast Cell-Mediated Orchestration of Airway Epithelial Responses in Chronic Respiratory Diseases

    Author : Frida Berlin; Respiratorisk cellbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mast cell; Tryptase; Chymase; Bronchial epithelium; Respiratory diseases;

    Abstract : Chronic respiratory diseases, such as asthma, are an increasing health issue worldwide and cause about 3.9 million deaths annually. Despite this, little is know about the molecular mechanisms underpinning disease pathogenesis. READ MORE

  7. 10. Defining the role of mast cells in guinea pig models of asthma

    Author : Jielu Liu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Asthma is a common respiratory disease characterized by several pathophysiological features, such as allergen induced bronchoconstriction (in allergic asthma), airway hyperresponsiveness (AHR), airway inflammation, airway remodeling and mast cell hyperplasia. An increase of mast cells has been found in asthma patients. READ MORE