Search for dissertations about: "albert heck"

Found 3 swedish dissertations containing the words albert heck.

  2. 1. Targeted proteomics methods for protein quantification of human cells, tissues and blood

    Author : Fredrik Edfors; Mathias Uhlén; Albert Heck; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; proteomics; mass spectrometry; protein quantification; stable isotope standard; parallel reaction monitoring; immuno-enrichment; Bioteknologi; Biotechnology;

    Abstract : The common concept in this thesis was to adapt and develop quantitative mass spectrometric assays focusing on reagents originating from the Human Protein Atlas project to quantify proteins in human cell lines, tissues and blood. The work is based around stable isotope labeled protein fragment standards that each represent a small part of a human protein-coding gene. READ MORE

  4. 2. On the analysis of antibody repertoires

    Author : August Jernbom Falk; Peter Nilsson; Anna Månberg; Albert J.R. Heck; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; antibody repertoire; autoantibodies; serology; microarray; bead array; affinity proteomics; psychosis; SARS-CoV-2; COVID-19; post-COVID-19 condition; immunoglobulin; IgG; Biotechnology; Bioteknologi;

    Abstract : The antibody repertoire is the ensemble of antibodies found in an individual at a given time. It displays high heterogeneity between individuals while being both largely temporally stable within an individual and rapidly responsive to immunological challenge. READ MORE

  5. 3. Gas-Phase Protein Structure Under the Computational Microscope : Hydration, Titration, and Temperature

    Author : Erik Marklund; David van der Spoel; Albert Heck; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular dynamics; gas phase; proteins; micelles; proton transfer; Grothuss mechanism; kinetics; Physics; Fysik; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : Although the native environment of the vast majority of proteins is a complex aqueous solution, like the interior of a cell, many analysis methods for assessing chemical and physical properties of biomolecules require the sample to be aerosolized; that is, transferred to the gas-phase. An important example is electrospray-ionization mass spectrometry, which can provide a wide range of information about e. READ MORE