Search for dissertations about: "albumins"
Found 4 swedish dissertations containing the word albumins.
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1. Oxygen delivery and mitochondrial dysfunction as assessed by microdialysis during interventions in experimental sepsis
Abstract : Early administration of broad-spectrum antibiotics is the first goal in sepsis treatment. Besides from bacteriostatic/bactericidal effects, some antibiotics may also modify the host´s response to infection. The novel antibiotic tigecycline may exert such properties; however, this property has not been evaluated in large-animal trials. READ MORE
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2. NMR Studies of Bacterial Albumin-Binding Modules
Abstract : Peptostreptococcus magnus and group C/G streptococci are Gram-positive cocci that are part of the normal flora and reside in more or less the same locations in the host. Protein G of group C/G streptococci was originally described as binding IgGFc of several species and later shown to also bind human serum albumin and albumins from various animal species. READ MORE
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3. Development of molecular recognition by rational and combinatorial engineering
Abstract : Combinatorial protein engineering, taking advantage of large libraries of protein variants and powerful selection technology, is a useful strategy for developing affinity proteins for applications in biotechnology and medicine. In this thesis, two small affinity proteins have been subjected to combinatorial protein engineering to improve or redirect the binding. READ MORE
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4. Studies of protein structure, dynamics and protein-ligand interactions using NMR spectroscopy
Abstract : In the first part of the thesis, protein-ligand interactions were investigated using the chaperone LcrH, from Yersinia as target protein. The structure of a peptide encompassing the amphipathic domain (residue 278-300) of the protein YopD from Yersinia was determined by NMR in 40% TFE. READ MORE