Search for dissertations about: "alpha particles"

Showing result 1 - 5 of 65 swedish dissertations containing the words alpha particles.

  2. 1. Cellular responses to combined irradiation with alpha particles and X-rays

    Author : Alice Sollazzo; Andrzej Wojcik; Alexandros Georgakilas; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Radiation; DNA damage; mutations; alpha particles; X-rays; mixed beam; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Mixed radiation fields, where different ionizing particles act together, are very important in radiobiology and in radiation protection. Mixed beams are not only the most common form of radiation exposure, but the prediction of their biological effect is also full of uncertainties. READ MORE

  4. 2. Tools for the Advancement of Radiopharmaceutical Therapy

    Author : Emma Mellhammar; Forskningsgruppen för Systemisk strålterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiopharmaceutical therapy; Nuclear medicine; Monte Carlo simulation; Intratherapeutic preclinical PET; Alpha particles; Beta Particles; radionuclides; Radiobiology; γ-H2AX; Dosimetry;

    Abstract : Radiopharmaceutical therapy is used to treat cancers and other diseases with radiolabeled pharmaceuticals. The treatment targets specific cells, and the emitted ionizing radiation cause cytotoxic damage. Dosimetry is performed to estimate the absorbed dose from the energy deposited in the body. READ MORE

  5. 3. Pretargeting agents and At-211-labeled effector molecules: Synthesis and preclinical evaluation for pretargeted alpha-radioimmunotherapy

    Author : Sofia Frost; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alpha particles; astatine-211; avidin; biotin; ovarian cancer; polylysine; pretargeted radioimmunotherapy;

    Abstract : .... READ MORE

  6. 4. Development of targeted alpha therapy with Bi-213 and At-211 for the treatment of disseminated cancer

    Author : Anna Gustafsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alpha particles; astatine; bismuth; MX35; ovarian cancer; polylysine; pretargeted radioimmunotherapy; radioimmunotherapy;

    Abstract : Radioimmunotherapy (RIT) is a type of targeted cancer therapy. The concept behind RIT is to deliver cytotoxic ionizing radiation to tumor cells by attaching radionuclides to tumor-specific antibodies. READ MORE

  7. 5. Astatine-211 radioimmunotherapy of ovarian cancer. Therapeutic efficacy, myelotoxicity, andradiation dosimetry in an animal model

    Author : Jörgen Elgqvist; Göteborgs universitet; []
    Keywords : astatine; alpha-particles; monoclonal antibodies; radioimmunotherapy; ; ovarian cancer; myelotoxicity; therapeutic efficacy; radiation dosimetry; fractionation;

    Abstract : Alpha-particle emitting radionuclides have recently obtained an increased attention whenconsidering new strategies for treating disseminated cancer. Astatine (211At), that emits alphaparticleswith a mean path length of 62 μm, a mean linear energy transfer (LET) of 111keV/Mum, and a half-life of 7. READ MORE