Search for dissertations about: "alpha-2 adrenergic receptor"

Found 4 swedish dissertations containing the words alpha-2 adrenergic receptor.

  2. 1. Alpha-2 Adrenergic Receptors and Signal Transduction : Effector Output in Relation to G-Protein Coupling and Signalling Cross-Talk

    Author : Johnny Näsman; Peter Evans; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; Adrenergic; receptor; G-protein; adenylyl cyclase; cAMP; calcium; cross-talk; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Abstract : The alpha-2 adrenergic receptor (α2-AR) subfamily includes three different subtypes, α2A-, α2B- and α2C-AR, all believed to exert their function through heterotrimeric Gi/o-proteins. The present study was undertaken in order to investigate subtype differences in terms of cellular response and to explore other potential signalling pathways of α2-ARs. READ MORE

  4. 2. Psychosocial stress in relation to blood pressure and cardivascular disease - epidemiological and genetic aspects

    Author : Bertil Öhlin; Internmedicin - epidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; receptor; Cardiovascular system; Medicin människa och djur ; Medicine human and vertebrates ; adrenergic; alpha-2; beta-1; mortality; morbidity; prospective; studies; polymorphism; work; stress; blood pressure; hypertension;

    Abstract : Psychosocial stress has been linked to both hypertension and cardiovascular disease (CVD), and hypertension has been proposed to be one mediator of the increased CVD risk in subjects reporting stress. Genetic susceptibility for blood pressure elevation in relation to stress has been proposed, but so far there is little evidence. READ MORE

  5. 3. Adrenergic control of small intestinal motility and blood flow : an experimental study in rat and man

    Author : Mikael Thollander; Karolinska Institutet; Karolinska Institutet; []
    Keywords : clonidine; computerized recording; intestinal blood flow; isoprenaline; laser Doppler flownretry; manometry; migrating motor complex; oxymetazoline; propranolol; small intestine;

    Abstract : Small intestinal motility in the fasted state is characterized by migrating motor complexes (MMCs). Both animals and man exhibit the MMC, which consists of periods of regular contractions, i.e. activity fronts, that migrate along the length of the small bowel and alternate with periods of quiescence. READ MORE

  6. 4. Impact of candidate genes on obesity and type 2 diabetes

    Author : Ewa-Carin Långberg; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Obesity and type 2 diabetes (T2D) have strong genetic components. Identification of susceptibility genes in both diseases will give better knowledge of their pathomechanisms and future therapies. READ MORE