Search for dissertations about: "alpha1-Antitrypsin deficiency"

Found 4 swedish dissertations containing the words alpha1-Antitrypsin deficiency.

2. 1. Characterization of Pleiotropic Activities of alpha1-Antitrypsin

   Author : Caroline Sandström; Enheten för kroniska inflammatoriska och degenerativa sjukdomar; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammation; alpha1-Antitrypsin deficiency; alpha1-Antitrypsin;

   Abstract : Chronic Obstructive Pulmonary Disease (COPD) is a respiratory disease characterized by chronic inflammatory response in the airways and lung parenchyma that involves the influx of inflammatory, structural cells and mediators. The inflammatory process resulting in lung tissue destruction, emphysema, includes the excess of uninhibited proteases released from inflammatory cells. READ MORE

4. 2. Lung function in alpha1-antitrypsin deficiency

   Author : Eeva Piitulainen; allergologi och palliativ medicin Lungmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alpha1-antitrypsin deficiency. Lung function. Register. Risk factors. Lung disease. Natural course.; Respiratory system; Andningsorganen;

   Abstract : Hereditary alpha1-antitrypsin (AAT) deficiency predisposes to liver disease and emphysema. The aims of the studies upon which thesis is based were to investigate the natural course of lung function and risk factors for lung disease in AAT-deficient adolescents (PiZZ and PiSZ) and adults (PiZZ), and to study clinical manifestations in AAT-deficient adults. READ MORE

5. 3. Arterial wall stiffness in man. On gender differences and abnormalities in insulin dependent diabetes mellitus and alpha1-antitrypsin deficiency

   Author : Åsa Rydén Ahlgren; Malmö Klinisk fysiologi och nuklearmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sex characteristics.; abdominal aortic aneurysm; arterial stiffness; alpha1-antitrypsin deficiency; ultrasonography; Insulin dependent diabetes mellitus; Clinical physics; radiology; tomography; medical instrumentation; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering;

   Abstract : The mechanical properties of major arteries may reflect early manifestations of vascular disease and are also of interest because they are important for cardiac work. Using echo-tracking sonography and blood pressure measurements, arterial stiffness and diameters were investigated in healthy individuals as well as in patients with insulin dependent diabetes mellitus (IDDM) or alpha1-antitrypsin deficiency (alpha1-AT deficiency). READ MORE

6. 4. Serine protease inhibitors in the upper and lower airways

   Author : Camilla Hollander; Enheten för kroniska inflammatoriska och degenerativa sjukdomar; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; auditive system and speech; Neutrophils; audiology; Otorhinolaryngology; Medicin människa och djur ; AAT; Medicine human and vertebrates ; SLPI; cytokines chemokines; anti-proteases; audiologi; hörsel- och talorganen; Airway inflammation; Otorinolaryngologi;

   Abstract : Proteases and their inhibitors are implicated in the physiology and pathology of the airways. Protease inhibitors include those produced locally, such as secretory leukocyte protease inhibitor (SLPI), and those produced mainly by the liver that can reach the airways via passive diffusion, such as alpha1-antitrypsin (AAT). READ MORE