Search for dissertations about: "alternative splicing"

Showing result 1 - 5 of 105 swedish dissertations containing the words alternative splicing.

  1. 1. Regulation of adenovirus alternative pre-mRNA splicing Functional characterization of exonic and intronic splicing enhancer elements

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Bai-Gong Yue; Uppsala universitet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; adenovirus; pre-mRNA splicing; splicing enhancer; MLTU; L1; SR protein; ASF SF2; E. coli; phosphorylation; dephosphorylation; Biokemi; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi; mikrobiologi; Microbiology;

    Abstract : Pre-mRNA splicing and alternative pre-mRNA splicing are key regulatory steps controlling geneexpression in higher eukaryotes. The work in this thesis was focused on a characterization of thesignificance of exonic and intronic splicing enhancer elements for pre-mRNA splicing. READ MORE

  2. 2. Regulation of Human Papillomavirus Type 16 Late L1 mRNA Splicing

    University dissertation from Division of Medical Microbiology, Lund University

    Author : Xiaoze Li; Lunds universitet.; Lund University.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HPV-16; cervical cancer; RNA processing; alternative splicing; splicing enhancer; splicing silencer; viral persistance; SR proteins; hnRNP proteins;

    Abstract : Popular Abstract in English Each year an estimated 530 000 new cases of cervical cancer are diagnosed and more than 275 000 women die from cervical cancer worldwide (2). Cervical cancer is caused by sexually-acquired infections with a subset of human papillomavirus (HPV) (359, 360). READ MORE

  3. 3. The Adenovirus L4-33K Protein A Key Regulator of Virus-specific Alternative Splicing

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Heidi Törmänen Persson; Uppsala universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; L4-33K; adenovirus; splicing; phosphorylation; localization; replication centers; L4-22K; MLTU; DNA-PK; DNA-dependent protein kinase; PKA; cAMP-dependent protein kinase; transcription sites; SR protein; Medical Virology; Medicinsk virologi;

    Abstract : Adenoviruses have been extensively studied in the field of gene regulation, since their genes are subjected to a tightly controlled temporal expression during the virus lifetime. The early-to-late shift in adenoviral gene expression distinguishes two completely different programs in gene expression. READ MORE

  4. 4. The Modular Domain Structure of ASF/SF2: Significance for its Function as a Regulator of RNA Splicing

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Vita Dauksaite; Uppsala universitet.; [2003]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; pre-mRNA splicing; alternative splicing; splicing regulation; SR proteins; ASF SF2; modular domains; adenovirus; MLTU L1; E1A; MS2; Molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi;

    Abstract : ASF/SF2 is an essential splicing factor, required for constitutive splicing, and functioning as a regulator of alternative splicing. ASF/SF2 is modular in structure and contains two amino-terminal RNA binding domains (RBD1 and RBD2), and a carboxy-terminal RS domain. READ MORE

  5. 5. Alternative splicing of interleukin-7

    University dissertation from Stockholm : Karolinska Institutet, Department of Microbiology, Tumor and Cell Biology

    Author : Nalini Kumar Vudattu; Karolinska Institutet.; Karolinska Institutet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Alternative splicing of pre-mRNA is the primary source of creating proteome diversity in humans; it is therefore highly relevant to disease and therapy. Alternative splicing has been described for many cytokines and these splice variants appear to function as either agonists or as antagonists of the wildtype cytokine. READ MORE