Search for dissertations about: "alveolar clearance"

Showing result 1 - 5 of 12 swedish dissertations containing the words alveolar clearance.

2. 1. Development and regulation of alveolar fluid clearance in the guinea pig

   Author : Andreas Norlin; Biologiska institutionen; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; oxytocin-induced preterm labor; IRDS; fetal lung fluid; preterm lung development; amiloride-sensitive sodium channels; beta-adrenergic stimulation; alveolar epithelium; Animal physiology; Djurfysiologi;

   Abstract : Alveolar fluid clearance is driven by active absorption of Na+ across the alveolar epithelium. Development and hormonal regulation of alveolar fluid clearance over 1 hour was studied by instillation of a protein-containing, isosmolar fluid into lungs of fetal, newborn, and adult guinea pigs. READ MORE

4. 2. Phagolysosomal pH measurements in alveolar macrophages

   Author : Kristina Nyberg Lindborg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : alveolar clearance; alveolar macrophages; phagocytosis; phagolysosomal pH; respiratory burst; silica particles; S. cerevisiae; C. albicans;

   Abstract : Background: Mechanical clearance of insoluble particles from the alveolar part of the lung is known to be a slow process in humans, i. e., one or several years. Particles deposited in the alveolar region are phagocytized by alveolar macrophages (AM). READ MORE

5. 3. Pulmonary Injury Following Intestinal Ischemia and Reperfusion in Rats

   Author : Anna Börjesson; Lund Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reperfusion injury; intestinal ischemia; pulmonary injury; endothelium; cytokines; alveolar fluid clearance; leukocytes; orthopaedics; Surgery; traumatology; ortopedi; Kirurgi; traumatologi;

   Abstract : Intestinal ischemia and reperfusion (I/R) is a potentially life-threatening condition, sometimes leading to a systemic inflammatory response and the potential development of the multiple organ dysfunction syndrome. The overall aim of the thesis was to study the effects of intestinal I/R on pulmonary function with special emphasis on removal of excess alveolar fluid, pulmonary endothelial barrier permeability, leukocyte accumulation and function, and possible therapeutic strategies to prevent the development of pulmonary injury following intestinal I/R. READ MORE

6. 4. Heparin-binding protein and organ failure in critical illness

   Author : Jonas Tydén; Joakim Johansson; Magnus Hultin; Jakob Walldén; Sören Berg; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparin-binding protein; Critical care; Shock; Acute respiratory distress syndrome; Acute kidney injury; Ventilator induced lung injury; Renal clearance; Anaesthesiology; anestesiologi;

   Abstract : Background: For patients severely ill enough to require care in an intensive care unit (ICU), both the disease itself (e.g. bacteria in the blood in sepsis or fractures after trauma) and effects of the immune system can cause circulatory, pulmonary, or renal dysfunction. Leukocytes play a dominant role in the immune system. READ MORE

7. 5. Recognition and clearance of Streptococcus pneumoniae by the innate immune system

   Author : Katharina Beiter; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Streptococcus pneumoniae (the pneumococcus) is a major human pathogen causing diseases such as pneumonia, bacteremia or meningitis and constitutes a leading cause of morbidity and mortality worldwide. The pathogenesis of pneumococcal disease and the mechanisms of recognition and clearance of S. READ MORE