Search for dissertations about: "alveolar epithelial cells"

Showing result 1 - 5 of 36 swedish dissertations containing the words alveolar epithelial cells.

2. 1. Role of alveolar epithelial cells in macrophage responses against mycobacterial infections

   Author : Olga Daniela Chuquimia Flores; Carmen Fernández; Diana Boraschi; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Lung; alveolar epithelial cells; macrophages; AEC-derived media; control of intracellular bacterial growth; mycobacterial infections; immunologi; Immunology;

   Abstract : This thesis aimed to investigate the role of alveolar epithelial cells (AEC) on immune responses against mycobacterial infections, specifically, the role of AEC in modulating macrophage functions through the secretion of broad variety of factors.In paper I, we compared murine AEC with interstitial macrophages (PuM) in their ability to take up and control mycobacterial growth and their capacity as antigen-presenting cells. READ MORE

4. 2. Models of alveolar remodeling in chronic lung disease

   Author : Oskar Rosmark; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Extracellular matrix ECM ; Decellularization; Mass Spectrometry MS ; Biomechanics; Chronic obstructive pulmonary disease COPD ; Idiopathic pulmonary fibrosis IPF ; Alveolar epithelial cells; Fibroblasts; Lung slices;

   Abstract : Lung function is highly dependent on the structure of the lung parenchyma. Remodeling of the alveolar compartment is a central part of the pathology of chronic lung disease such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). READ MORE

5. 3. Functional importance of estrogen receptors in the periodontium

   Author : Daniel Nebel; Malmö högskola; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Estrogen; Estrogen receptors; LPS; Periodontium; PDL cells; Gingival epithelial cells;

   Abstract : Östrogen är ett kvinnligt könshormon som även har andra effekter. Östrogen verkar i cellkärnan genom att binda till en östrogenreceptor (ER), som finns i två olika typer, ERα och ERβ. Parodontit (tandlossning) är en inflammationssjukdom som drabbar tandens fäste som svar på bakterier som normalt finns i munhålan. READ MORE

6. 4. Functions of PDGF-A and -C. Essential ligands for the PDGF alpha receptor

   Author : Hans Boström; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelet-derived growth factor; PDGF-A; PDGF-C; PDGF alpha receptor; extracellular retention; gene targeting; mouse development; epithelial-mesenchymal interaction; lung; alveolar formation; spina bifida; gastrointestinal villus;

   Abstract : Altered protein kinase activity is a contributing factor in many diseases including most formsof human malignancies, and there is reason to believe that protein kinases will prove to be majordrug targets in the treatment of cancer. Protein kinases mediate most of the signal transduction ineukaryotic cells, regulating cellular events such as transcription, metabolism, proliferation,cytoskeletal rearrangement, migration, differentiation and apoptosis. READ MORE

7. 5. Mesenchymal heterogeneity in the adult human lung

   Author : Måns Kadefors; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lung; Extracellular matrix; Adventitia; Fibroblast; mesenchymal cell; Alveolar epithelial cell; Fibrosis; Idiopathic pulmonary fibrosis; Mass spectrometry; RNA-sequencing;

   Abstract : The human lung is a complex tissue consisting of a heterogeneous mix of different structures and cells, each which a specific role that together contribute to the primary function of the organ: the gas exchange. Different mesenchymal cells populate the interstitial areas around airways and blood vessels and form the connective tissue together with the extracellular matrix. READ MORE