Search for dissertations about: "alveolar macrophage"

Showing result 1 - 5 of 20 swedish dissertations containing the words alveolar macrophage.

2. 1. Role of alveolar epithelial cells in macrophage responses against mycobacterial infections

   Author : Olga Daniela Chuquimia Flores; Carmen Fernández; Diana Boraschi; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Lung; alveolar epithelial cells; macrophages; AEC-derived media; control of intracellular bacterial growth; mycobacterial infections; immunologi; Immunology;

   Abstract : This thesis aimed to investigate the role of alveolar epithelial cells (AEC) on immune responses against mycobacterial infections, specifically, the role of AEC in modulating macrophage functions through the secretion of broad variety of factors.In paper I, we compared murine AEC with interstitial macrophages (PuM) in their ability to take up and control mycobacterial growth and their capacity as antigen-presenting cells. READ MORE

4. 2. Function of B2-adrenoceptors on alveolar macrophages

   Author : Anita Zetterlund; Karolinska Institutet; Karolinska Institutet; []
   Keywords : A;

   Abstract : B2-Agonists are very effective drugs for bronchodilatation, provide a rapid relief of symptoms in asthma, and are recommended as first line treatment, together with steroids. The relaxation of bronchial smooth muscles is a well-established effect of B-agonists, but their effects on inflammatory cells in the airways are less certain. READ MORE

5. 3. Role of macrophage receptor MARCO in host defense

   Author : Marko Sankala; Karolinska Institutet; Karolinska Institutet; []
   Keywords : MARCO; innate immunity; scavenger receptor.;

   Abstract : Innate immunity, the first line of defense against infectious microorganisms, appeared early in evolution. Innate immunity relies on specialized cells such as macrophages that are the first to encounter pathogens during infection. READ MORE

6. 4. Defense and inflammation by alveolar macrophages in response to inhaled fungi

   Author : Khairun Nessa; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Alveolar macrophage; Candida and Aspergillus species; C. neoformans; phagocytosis; oxidative metabolism; phagolysosomal pH; cytokines.;

   Abstract : Background: Serious fungal infections have increased notably in patients receiving modern treatment like organ transplantation, parenteral nutrition, long term steroid therapy and broad spectrum antibiotics. Patients with HIV infections and drug addicts also contract fungal infections. READ MORE

7. 5. Pulmonary Injury Following Intestinal Ischemia and Reperfusion in Rats

   Author : Anna Börjesson; Lund Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reperfusion injury; intestinal ischemia; pulmonary injury; endothelium; cytokines; alveolar fluid clearance; leukocytes; orthopaedics; Surgery; traumatology; ortopedi; Kirurgi; traumatologi;

   Abstract : Intestinal ischemia and reperfusion (I/R) is a potentially life-threatening condition, sometimes leading to a systemic inflammatory response and the potential development of the multiple organ dysfunction syndrome. The overall aim of the thesis was to study the effects of intestinal I/R on pulmonary function with special emphasis on removal of excess alveolar fluid, pulmonary endothelial barrier permeability, leukocyte accumulation and function, and possible therapeutic strategies to prevent the development of pulmonary injury following intestinal I/R. READ MORE