Search for dissertations about: "alzheimer disorder"
Showing result 1 - 5 of 25 swedish dissertations containing the words alzheimer disorder.
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1. Allergy and Alzheimer disease
Abstract : Alzheimer disease (AD) is a neurodegenerative disorder characterized by progressive dementia with devastating effects for the patients and their families. The treatments available are purely symptomatic and there is need for treatment strategies aiming at the etiopathogenesis of AD. READ MORE
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2. Biomarkers in preclinical familial Alzheimer disease
Abstract : Background: Alzheimer disease (AD) is a neurodegenerative disorder, characterized by the accumulation of b-amyloid (Ab) plaques and tangles consisting of hyperphosphorylated tauprotein in the brain. It accounts for 60-70% of dementia cases, making it the most common cause of dementia. READ MORE
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3. Statin treatment and beta-Amyloid Production in Patients with Alzheimer s Disease
Abstract : Alzheimer s disease (AD) is a progressive neurodegenerative disorder pathologically characterized by neurofibrillary tangles and amyloid plaques. According to the amyloid cascade hypothesis, the increased production of beta-amyloid (Abeta), derived form the amyloid precursor protein (APP), and its aggregation into plaques are key pathological events, driving neurodegeneration in AD. READ MORE
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4. Pathogenic Mechanisms of the Arctic Alzheimer Mutation
Abstract : Alzheimer’s disease (AD) is a progressive neurodegenerative disorder, neuropathologically characterized by neurofibrillay tangles and deposition of amyloid-β (Aβ) peptides. Several mutations in the gene for amyloid precursor protein (APP) cause familial AD and affect APP processing leading to increased levels of Aβ42. READ MORE
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5. Intracellular dynamics of Alzheimer disease-related proteins
Abstract : Alzheimer’s disease is a devastating neurodegenerative disorder characterized by accumulation of amyloid-β peptide and formation of amyloid plaques and aggregates of hyperphosphorylated tau protein forming neurofibrillary tangles. The amyloid-β peptide is generated through sequential processing of the amyloid precursor protein (APP) by β- and γ-secretase. READ MORE