Search for dissertations about: "alzheimer"

Showing result 1 - 5 of 171 swedish dissertations containing the word alzheimer.

  2. 1. Allergy and Alzheimer disease

    Author : Heela Sarlus; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Alzheimer disease (AD) is a neurodegenerative disorder characterized by progressive dementia with devastating effects for the patients and their families. The treatments available are purely symptomatic and there is need for treatment strategies aiming at the etiopathogenesis of AD. READ MORE

  4. 2. The Alzheimer Aβ Peptide : Identification of Properties Distinctive for Toxic Prefibrillar Species

    Author : Anna-Lena Göransson; Jenny Presto; Linköpings universitet; []
    Keywords : ;

    Abstract : Proteins must have specific conformations to function correctly inside cells. However, sometimes they adopt the wrong conformation, causing dysfunction and disease. A number of amyloid diseases are caused by misfolded proteins that form amyloid fibrils. One such disease is Alzheimer’s disease (AD). READ MORE

  5. 3. Thioredoxin-1 in Alzheimer disease

    Author : Torbjörn Persson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Oxidative stress is one of the earliest signs in Alzheimer Disease (AD) brain. In order to protect themselves against oxidative stress, neurons use antioxidants as a defense mechanism. Such an antioxidant is Thioredoxin-1 (Trx1). Previous studies have shown that the levels of Trx1 are reduced in the brains of AD patients. READ MORE

  6. 4. PresequenceProtease (PreP), a novel Peptidasome in Mitochondria and Chloroplasts : Localization, Function, Structure and Mechanism of Proteolysis

    Author : Shashi Bhushan; Elzbieta Glaser; Johannes Herrmann; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein import; mitochondria; chloroplasts; PresequenceProtease; Alzheimer; Biochemistry; Biokemi; biokemi; Biochemistry;

    Abstract : The information for mitochondrial and chloroplastic protein import and targeting generally resides in the N-terminal part of the protein, called a targeting peptide. The targeting peptide is cleaved off by the organellar processing peptidases after import of a precursor protein. READ MORE

  7. 5. Odor identification in aging and dementia : Influences of cognition and the ApoE gene

    Author : Jonas Olofsson; Steven Nordin; Maria Larsson; Richard Doty; Umeå universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Aging; olfaction; identification; dementia; Alzheimer; genetics; ApoE; population based; cognition; demographics; Psychology; Psykologi;

    Abstract : Olfactory function is impaired in aging and dementia. The general aim of this thesis was to identify variables that predict olfactory function and dysfunction (assessed with an odor identification test) in middle-aged and elderly adults. READ MORE