Search for dissertations about: "amino acid derivative"

Showing result 11 - 15 of 23 swedish dissertations containing the words amino acid derivative.

  2. 11. Light-Triggered Conformational Switches for Modulation of Molecular Recognition : Applications for Peptidomimetics and Supramolecular Systems

    Author : Magnus Blom; Adolf Gogoll; Morten Grötli; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bisporphyrin tweezers; peptidomimetics; host-guest systems; conformational analysis; supramolecular chemistry; photochemistry; Organisk kemi; Organic Chemistry; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Abstract : The main focus of this thesis is on photochemical modulation of molecular recognition in various host-guest systems. This involves the design, synthesis and integration of light-triggered conformational switches into peptidomimetic guests and molecular tweezer hosts. READ MORE

  4. 12. Synthesis of inositolphosphoglycans found in Trypanosoma cruzi and development of novel carbohydrate monomolecular layers

    Author : Markus Hederos; Robert Madsen; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : In this thesis, synthetic carbohydrate chemistry has been utilized to contribute to the fundamental understanding of three biological relevant areas. These include parasite cell-membrane glycoconjugates, protein-resistant surfaces and antifreeze glycoproteins. READ MORE

  5. 13. Applications of multi-component condensations and development of polyamine synthesis on solid-phase

    Author : Daniel Jönsson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Abstract : Solid-phase synthesis of small non-polymeric molecules has become increasingly important as a tool in the development of pharmacologically active compounds. Of particular interest are the syntheses of compounds with low molecular weight, low polarity and a reduced flexibility of the functional groups, i.e. READ MORE

  6. 14. Synthetic development towards benzodiazepine alkaloids : total synthesis of circumdatin F and C

    Author : Anette Witt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Alkaloids; benzodiazepines; cyclisation; Michael reactions; quinazolinones; synthesis.;

    Abstract : Benzodiazepine alkaloids exhibit a multitude of interesting pharmacological activities. This thesis deals with the development of synthetic methods towards such alkaloids, of which the main efforts can be divided into three parts. READ MORE

  7. 15. Polypeptide Conjugates as High-affinity Binders for Proteins

    Author : Lotta Tollstoy Tegler; Lars Baltzer; Amelie Eriksson Karlström; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein recognition; polypeptide conjugates; peptide; molecular interactions; C-reactive protein; Acetylcholine esterase; Human Carboinc anhydrase; Chemistry; Kemi; organisk kemi; Organic Chemistry;

    Abstract : A novel concept for protein recognition has been developed. The recognition unit is a hybrid molecule obtained by conjugation of a small organic molecule to a synthetic polypeptide selected from a 16-membered set of 42 amino acid residue sequences. The sequences are unordered and have no prior relation to the target proteins. READ MORE