Search for dissertations about: "amino acid starvation"

Showing result 16 - 20 of 20 swedish dissertations containing the words amino acid starvation.

  1. 16. The GH/IGF-1 system during surgery and catabolism : focus on metabolism and heart function

    Author : Mats Wallin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : GH plays a role in both anabolism and catabolism. The anabolic properties of GH are mediated by circulating (endocrine) and locally secreted (paracrine) IGF-1. It is thus the IGF-1 response after increased GH secretion that determines whether metabolism will be anabolic or catabolic. READ MORE

  2. 17. A holistic view on transcriptional regulatory networks in S. cerevisiae: Implications and utilization

    Author : David Bergenholm; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Transcription factors; S. cerevisiae; chemostat; transcriptomics; regulatory networks;

    Abstract : Life; perhaps it is bold to start an abstract with this powerful word, but this is where I will start. My research is at the heart of life. READ MORE

  3. 18. Detection, transfer and role of an environmentally spread neurotoxin (BMAA) with focus on cyanobacteria and the Baltic Sea region

    Author : Lotta Berntzon; Birgitta Bergman; Geoffrey Codd; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; β-N-methylamino-L-alanine; BMAA; cyanobacteria; Baltic Sea; blooms; neurotoxin; neurodegenerative diseases; amyotrophic lateral sclerosis; ALS; nitrogenase; nitrogen fixation; Plant Physiology; växtfysiologi;

    Abstract : β-N-methylamino-L-alanine (BMAA) is one of the more recently discovered bioactive compounds produced by cyanobacteria. BMAA is a non-protein amino acid reported present in human brain tissues of patients deceased from a neurodegenerative disease, such as Alzheimer´s disease or amyotrophic lateral sclerosis (ALS). READ MORE

  4. 19. The role of autophagy in anticancer therapy

    Author : Matheus Dyczynski; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Autophagy is a fundamental catabolic process, which is utilized by nearly every cell and tissue type upon stress exposure and has been shown to contribute to resistance to chemotherapy in a variety of cancers. The subject of this thesis is to shed light on the role of autophagy in chemotherapy and to investigate novel regulators of autophagy. READ MORE

  5. 20. Bioinformatics, evolution and revolution in our understanding of toxin-antitoxin systems

    Author : Chayan Kumar Saha; Gemma C. Atkinson; Victoria Shingler; Gipsi Lima Mendez; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Bioinformatics; Alarmones; Evolution; Gene neighbourhood; Toxin; Antitoxin; molekylärbiologi; Molecular Biology;

    Abstract : Bacteria experience a wide range of natural challenges during their life cycles, to which they must respond and adapt to live. Under stressed conditions such as amino acid starvation, bacteria slow down their growth mechanism by producing small alarmone nucleotides guanosine pentaphosphate (pppGpp) and tetraphosphate (ppGpp), collectively referred to as (p)ppGpp. READ MORE