Advanced search

Found 1 swedish dissertation matching the above criteria.

2. 1. Structural and Biochemical Studies of Antibiotic Resistance and Ribosomal Frameshifting

   Author : Yang Chen; Maria Selmer; Dominique Fourmy; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein synthesis; elongation; elongation factor G; fusidic acid; antibiotic resistance; aminoglycoside adenyltransferase; ribosomal frameshifting; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

   Abstract : Protein synthesis, translation, performed by the ribosome, is a fundamental process of life and one of the main targets of antibacterial drugs. This thesis provides structural and biochemical understanding of three aspects of bacterial translation.Elongation factor G (EF-G) is the target for the antibiotic fusidic acid (FA). READ MORE