Search for dissertations about: "aminoglycosides"

Showing result 1 - 5 of 18 swedish dissertations containing the word aminoglycosides.

  1. 1. Regulation of Mammalian Poly(A) Polymerase Activity

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Ann-Charlotte Thuresson; Uppsala universitet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicine; poly A polymerase; PAP; polyadenylation; isoforms; phosphorylation; alternative splicing; CPSF interaction; aminoglycosides; Biomedicin; MEDICINE Microbiology; immunology; infectious diseases Microbiology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Poly(A) polymerase (PAP) is the enzyme catalyzing the synthesis of the adenine tail to the 3’-end of mRNA. This A-tail is present on the majority of the primary RNA transcripts of protein-coding genes, and is important for mRNA stability, export to the cytoplasm and translation. Therefore, PAP is a key regulator of eukaryotic gene expression. READ MORE

  2. 2. Pharmacokinetics and pharmacodynamics of aminoglycosides

    University dissertation from Linköping : Linköpings universitet

    Author : Barbro Isacsson; Linköpings universitet.; Linköpings universitet.; Linköpings universitet.; [1992]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Abstract : The pharmacokinetics of amikacin in humans and the pharmacodynamic effects, i.e. initial killing and postantibiotic effect (P AE), of the aminoglycosides were studied in this thesis. READ MORE

  3. 3. Applications of organ culture of the mouse inner ear

    University dissertation from Umeå : Umeå universitet

    Author : Diana Berggren; Umeå universitet.; Umeå universitet.; [1991]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; organ culture; embryonic inner ear; intercellular junctions; aminoglycosides; statoacoustic ganglion; intermediate filaments; collagen; endolymph;

    Abstract : The embryonic mouse inner ear was used as a model with which to study ototoxicity and tissue interactions. The inner ear anlage can be explanted and cultured in vitro from about the 12th gestational day (gd), and will differentiate parallel with the inner ear developing in vivo until a time corresponding to birth (21st gd). READ MORE

  4. 4. Antibiotic-induced Bacterial Toxin Release – Inhibition by Protein Synthesis Inhibitors

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Gunilla Hjerdt-Goscinski; Uppsala universitet.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; Endotoxin; LPS; exotoxin; SpeA; penicillin-binding protein; aminoglycosides; clindamycin; β-lactam antibiotics; severe sepsis; septic shock; Infektionssjukdomar; MEDICINE Microbiology; immunology; infectious diseases Infectious diseases; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Infektionssjukdomar;

    Abstract : Toxic products, such as endotoxin from the gram-negative and exotoxin from the gram-positive bacteria, are the most important initiators of the inflammatory host response in sepsis. In addition to antibacterial treatment, numerous attempts have been made to interfere with the exaggerated proinflammatory cascade initiated by the toxins. READ MORE

  5. 5. Serum Amyloid A Protein (SAA) in Healthy and Infected Individuals

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Anders Lannergård; Uppsala universitet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; acute phase proteins; adult; Administration Oral; aminoglycosides; amyloidosis; antibiotics; bacterial infections; body temperature; C-reactive protein; cefuroxime; cystitis; cytokines; elderly; infant; interleukin-6; newborn; pyelonephritis; serum amyloid A protein; virus diseases; Infektionssjukdomar; MEDICINE Microbiology; immunology; infectious diseases Infectious diseases; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Infektionssjukdomar;

    Abstract : Serum amyloid A protein (SAA) is an acute phase protein that has recently gained increasing interest as a potential marker for disease and treatment monitoring. We investigated SAA and CRP levels in (a) patients with various common infectious diseases (n=98), (b) patients with pyelonephritis (n=37) versus patients with cystitis (n=32), (c) healthy individuals of varying ages (n=231), (d) very immature newborn infants with or without nosocomial infections (NIs) (n=72) and (e) patients with bacterial infections treated with cefuroxime (n=81). READ MORE