Search for dissertations about: "aminoglycosides"
Showing result 6 - 10 of 27 swedish dissertations containing the word aminoglycosides.
-
6. Serum Amyloid A Protein (SAA) in Healthy and Infected Individuals
Abstract : Serum amyloid A protein (SAA) is an acute phase protein that has recently gained increasing interest as a potential marker for disease and treatment monitoring. We investigated SAA and CRP levels in (a) patients with various common infectious diseases (n=98), (b) patients with pyelonephritis (n=37) versus patients with cystitis (n=32), (c) healthy individuals of varying ages (n=231), (d) very immature newborn infants with or without nosocomial infections (NIs) (n=72) and (e) patients with bacterial infections treated with cefuroxime (n=81). READ MORE
-
7. Pharmacometric Models for Antibacterial Agents to Improve Dosing Strategies
Abstract : Antibiotics are among the most commonly prescribed drugs. Although the majority of these drugs were developed several decades ago, optimal dosage (dose, dosing interval and treatment duration) have still not been well defined. READ MORE
-
8. Antibiotic Resistance and the Cellular Currency S-adenosyl-methionine : Modification of aminoglycosides and nucleic acids
Abstract : Streptomycin and spectinomycin are antibiotics that bind to ribosomes and inhibit protein synthesis. Common resistance mechanisms involve enzymatic modification of the two drugs by aminoglycoside nucleotidyltransferases (ANTs). The first part of this thesis covers the structural mechanism of two ANT enzymes. READ MORE
-
9. Modulating Organ Dysfunction in Experimental Septic Shock : Effects of Aminoglycosides, Antiendotoxin Measures and Endotoxin Tolerance
Abstract : Sepsis is a common diagnose in the intensive care population, burdened with a high mortality. The systemic inflammatory reaction underlying the development of septic organ dysfunction can be modeled using Gram-negative bacterial lipopolysaccharide, endotoxin. READ MORE
-
10. On the development of low level resistance in gram-positive and gram-negative bacteria after antibiotic exposure
Abstract : Resistance has been found to develop and spread via several mechanisms against virtually all clinically available antimicrobial agents. Increasing use of antibiotics has been shown to correlate to increasing incidence of bacterial resistance. READ MORE