Search for dissertations about: "amodiaquine"

Showing result 1 - 5 of 17 swedish dissertations containing the word amodiaquine.

  2. 1. Development of Analytical Methods for the Determination of Antimalarials in Biological Fluids

    Author : Daniel Blessborn; Yngve Bergqvist; Anders Helander; Högskolan Dalarna; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Malaria; Chloroquine; Quinine; Sulfadoxine; Pyrimethamine; Mefloquine; Lumefantrine; Amodiaquine; Pyronaridine; Proguanil; Atovaquone; Sampling paper; Dried blood spots; Capillary blood; Antimalarial drugs; Solid-phase extraction; Liquid chromatography.; Chemistry;

    Abstract : The aim of this thesis was to develop analytical methods for measuring antimalarial drugs in biological fluids. Solid phase extraction (SPE) was used for the enrichment and purification of the drugs. READ MORE

  4. 2. Development of Field-adapted Analytical Methods for the Determination of New Antimalarial Drugs in Biological Fluids

    Author : Niklas Lindegårdh; Karin Markides; Yngve Bergqvist; Anders Colmsjö; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; LC; liquid chromatography; biological samples; SPE; solid phase extraction; validation; antimalarial drugs; amodiaquine; piperaquine; atovaquone; dried blood spots; Analytisk kemi; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Abstract : This thesis deals with the development of analytical methods for the determination of new antimalarial drugs in biological fluids. The goal was to develop methods that facilitate clinical studies performed in the field, such as capillary blood sampling onto sampling paper. READ MORE

  5. 3. Development of field-adapted analytical methods for the determination of new antimalarial drugs in biological fluids

    Author : Niklas Lindegårdh; Högskolan Dalarna; []
    Keywords : LC; liquid chromatography; biological samples; SPE; solid phase extraction; validation; antimalarial drugs; amodiaquine; piperaquine; atovaquone; dried blood spots;

    Abstract : .... READ MORE

  6. 4. Plasmodium falciparum resistance to amodiaquine in monotherapy and in combination therapy with artesunate

    Author : Gabrielle Holmgren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In response to the increasing resistance to antimalarial monotherapies, artemisinin basedcombination therapy (ACT) is now recommended as first line therapy against uncomplicatedPlasmodium falciparum malaria. However, the choice of partner drug to artemisinin (ART) iscritical for ACT efficacy to endure. READ MORE

  7. 5. Development of Analytical Methods for Measurement of Drugs against Malaria in Plasma and Whole Blood

    Author : Daniel Blessborn; Högskolan Dalarna; []
    Keywords : Malaria Method Development Pyronaridine Atovaquone Proguanil Malarone Amodiaquine;

    Abstract : The aim of this thesis was to develop analytical methods for measuring drugs in blood and/or plasma. Solid phase extraction was used for the enrichment and purification of the drugs from the sample matrix. READ MORE