Search for dissertations about: "ampk"

Showing result 21 - 25 of 58 swedish dissertations containing the word ampk.

  1. 21. Central and peripheral mechanisms regulating energy and glucose homeostasis

    Author : Robby Zachariah Tom; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Obesity is a major health concern across the globe and is often associated with insulin resistance and type 2 diabetes. The coupling of ene rgy intake and expenditure is tightly regulated by central and peripheral mechanisms and is dysregulated in obesity. READ MORE

  2. 22. Novel pharmaceutical approaches to regulate glucose homeostasis

    Author : Maj Sundbom; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The Western sedentary life-style and calorie excess is causing an increased incidence of obesity and type 2 diabetes. When untreated, these diseases are associated with heart- and vascular disease, stroke, cancer, neuropathic pain, renal failure and infertility. READ MORE

  3. 23. Regulation of whole-body glucose and lipid metabolism by skeletal muscle

    Author : Milena Schönke; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Obesity and associated diseases like type 2 diabetes are rapidly growing health concerns across the globe. The uptake and expenditure of energy in the body are tightly regulated by a plethora of enzymes and hormones in central and peripheral tissues. READ MORE

  4. 24. Skeletal muscle plasticity and energy metabolism

    Author : Leonidas S Lundell; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Skeletal muscle is remarkable in its ability to adjust to our needs. It can change its energy stores and usage, as well as its total mass. Furthermore, skeletal muscle adapts to deactivate reactive oxygen species produced, which in turn can both damage cells and convey signals. READ MORE

  5. 25. Studies on exercise and glycogen re-synthesis in skeletal muscles of pigs with the PRKAG3 mutation

    Author : Anna Granlund; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : AMP-activated protein kinase (AMPK) plays an important role in the regulation of glucose and lipid metabolism in skeletal muscle. Many pigs of Hampshire origin have a naturally occurring mutation situated in the PRKAG3 gene which encodes a muscle-specific isoform of the AMPK γ3-subunit. READ MORE