Search for dissertations about: "amplicon sequencing"

Showing result 1 - 5 of 35 swedish dissertations containing the words amplicon sequencing.

  1. 1. Tagging systems for sequencing large cohorts

    Author : Mårten Neiman; Afshin Ahmadian; Peter Savolainen; KTH; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; next generation sequencing; genotyping; massive parallel sequencing; 454; Pyrosequencing; amplicon sequencing; enrichment; DNA barcodes; Genetics; Genetik;

    Abstract : Advances in sequencing technologies constantly improves the throughput andaccuracy of sequencing instruments. Together with this development comes newdemands and opportunities to fully take advantage of the massive amounts of dataproduced within a sequence run. READ MORE

  2. 2. Culture-independent methods and high-throughput sequencing applied to evolutionary microbial genomics

    Author : Anders E. Lind; Thijs JG Ettema; Purificación López-García; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Single cell genomics; metagenomics; amplicon; archaea; haloarchaea; endosymbiosis; ciliate; hydrogenosome; tree reconciliation;

    Abstract : Culture-independent methods allow us to better understand the diversity of microorganisms on earth. By omitting the culturing step, we can gain access to species previously out of our reach.To better capture and understand the diversity of microorganisms, we have developed an alternative to 16S amplicon sequencing. READ MORE

  3. 3. Next Generation Sequencing for Measurable Residual Disease Detection in Acute Myeloid Leukemia

    Author : Erik Delsing Malmberg; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute myeloid leukemia; minimal residual disease; massively parallel sequencing; next generation sequencing; NPM1; alloHCT;

    Abstract : Acute myeloid leukemia (AML) is the most common form of acute leukemia and generally associated with a poor prognosis. For both children and adults, the treatment is based on chemotherapy. Allogeneic hematopoietic stem cell transplant (alloHCT) is reserved for patients with intermediate or high risk of relapse, due to its associated risks. READ MORE

  4. 4. Microbial biofilm communities associated with degradation of sprayed concrete in subsea tunnels

    Author : Sabina Karacic; Chalmers University of Technology; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; metagenomics.; concrete; surface structure; marine environment; steel fibers; microbially induced deterioration; amplicon sequencing; biofilm; subsea tunnels;

    Abstract : Deterioration of concrete leads to reduced structural strength implying high societal challenge with huge economic impact. In the Oslofjord subsea tunnel, complex microbial biofilm activity together with abiotic attack from saline groundwater are responsible for concrete matrix degradation and steel fiber corrosion. READ MORE

  5. 5. Exploration of bacteria associated with Anopheles mosquitoes around the world : For the prevention of transmission of malaria

    Author : Louise K. J. Nilsson; Olle Terenius; Staffan Svärd; Sebastian Håkansson; Michael Strand; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; microbiota; microbiome; vector-borne disease; 16S rRNA gene; amplicon sequencing; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : Every year, hundreds of thousands of people die from malaria. Malaria is a disease caused by parasites, which are spread by female vector mosquitoes of the genus Anopheles. Current control measures against malaria are based on drugs against the parasites and vector control using insecticides. READ MORE