Search for dissertations about: "amyloid lipid"
Showing result 1 - 5 of 46 swedish dissertations containing the words amyloid lipid.
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1. alpha-synuclein: amyloid fibrils and interactions with lipid membranes
Abstract : The second most common neurodegenerative disease, Parkinson’s disease, is linked with an amyloid forming protein, alpha-synuclein. Hallmarks of Parkinson’s disease are progressive loss of dopaminergic neurons and accumulation of intraneuronal inclusions termed Lewy bodies. READ MORE
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2. α-synuclein interactions with lipid membranes
Abstract : α-synuclein is an intrinsically disordered protein implicated in synaptic vesicle trafficking at the synapse. Accumulation of α-synuclein in the form of amyloid deposits coincides with the loss of dopaminergic neurons in Parkinsons disease. READ MORE
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3. Co-assembly of proteins and lipids : From lipodiscs to amyloid aggregates
Abstract : Assemblies of different molecules is a prevalent phenomenon in nature, and crucial in biological life. Most of the biological assemblies are co-assembledcomposites, made up from several different components, either of thesame biomolecular type or a combination of different ones. READ MORE
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4. Development of MALDI Mass Spectrometry Imaging Methods for Probing Spatial Lipid Biochemistry of Amyloid Plaques in Alzheimer's Disease
Abstract : Alzheimer’s disease (AD) is the most prevalent cause of neurodegenerative dementia. Aggregation of amyloid β (Aβ) peptides into extracellular Aβ plaques is one of the major neuropathological features of AD. READ MORE
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5. Development of the Amyloid Fibril Characterisation Toolbox - New use for old dyes
Abstract : Amyloid fibrils are self-assembled protein homopolymers that playcentral roles in the pathology of several human diseases, most notably in progressiveneurodegenerative diseases such as Alzheimer’s disease (AD). In AD, fibrils areformed by the amyloid-β (Aβ) peptide, an enzymatic cleavage product that is naturallyproduced in human brain tissue. READ MORE