Search for dissertations about: "amyotrophic lateral sclerosis"

Showing result 1 - 5 of 75 swedish dissertations containing the words amyotrophic lateral sclerosis.

  1. 1. Superoxide dismutase 1 and amyotrophic lateral sclerosis

    Author : P. Andreas Jonsson; Stefan L. Marklund; David R. Borchelt; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; aggregates; ALS; amyotrophic lateral sclerosis; cerebrospinal fluid; disulfide-reduced; inclusions; misfolded; protective factor; SOD1; transgenic; Neurovetenskap; Neurology; Neurologi; Clinical Chemistry; klinisk kemi;

    Abstract : Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease affecting motor neurons in the spinal cord, brain stem and motor cortex, leading to paralysis, respiratory failure and death. In about 5% of ALS cases, the disease is associated with mutations in the CuZn-superoxide dismutase (hSOD1) gene. READ MORE

  2. 2. Neurodegeneration in amyotrophic lateral sclerosis : neurotrophic factors and monoamine oxidase B

    Author : Jonas Ekblom; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  3. 3. Autoantibodies in amyotrophic lateral sclerosis

    Author : Ratana Sindhuphak; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : .... READ MORE

  4. 4. Transmethylation, Polyamines and Apoptosis in Amyotrophic Lateral Sclerosis

    Author : Titti Ekegren; Håkan Askmark; Cecilia Gomes-Trolin; Sten-Magnus Aquilonius; Christopher Fowler; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; amyotrophic lateral sclerosis; neurodegeneration; transmethylation; polyamine; apoptosis; Neurovetenskap; Neurology; Neurologi;

    Abstract : Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive disorder characterized by degeneration of motor neurons in the cortex, brainstem and spinal cord. The patients usually die within 3-5 years after onset. The full etiology of ALS is unknown and many hypotheses have been proposed to explain the neurodegeneration. READ MORE

  5. 5. Of mice and men : SOD1 associated human amyotrophic lateral sclerosis and transgenic mouse models

    Author : Karin Sixtensdotter Graffmo; Thomas Brännström; Stefan Marklund; Elisabeth Englund; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aggregates; ALS; amyotrophic lateral sclerosis; inclusions; misfolded; vacuolisation; SOD1; transgenic; Pathology; Patologi;

    Abstract : Amyotrophic lateral sclerosis, ALS, is a progressive fatal neurodegenerative disorder affecting motor neurones in motor cortex, brain stem and spinal cord. This inevitably leads to paralysis, respiratory failure and death. READ MORE