Search for dissertations about: "amyotrophic lateral sclerosis"

Showing result 21 - 25 of 86 swedish dissertations containing the words amyotrophic lateral sclerosis.

  2. 21. Metabolic disorders in the etiology of amyotrophic lateral sclerosis : an epidemiological approach

    Author : Daniela Mariosa; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by a loss of motor neurons in the brain and spinal cord, leading to progressive muscle weakness in multiple regions of the body. No effective treatment is available and the disease progresses rapidly to death with an average survival time of 3-5 years after symptom onset. READ MORE

  4. 22. Amyotrophic lateral sclerosis and multiple sclerosis associated neuroinflammation : nationwide epidemiological studies on etiology, comorbidities, and treatment

    Author : Elisa Longinetti; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Amyotrophic lateral sclerosis (ALS) is a relatively rare but fatal neurodegenerative disease characterized by progressive muscle paralysis, due to loss of upper and lower motor neurons. Signs of neuroinflammation have been reported in ALS, however it is still unknown whether neuroinflammation is a cause or a consequence of the motor neuron dysfunction. READ MORE

  5. 23. Studies on the phenotype of LXRβ-/- mice : from malabsorption to amyotrophic lateral sclerosis

    Author : Chiara Gabbi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Liver X Receptors, LXRalpha and LXRbeta (NR1H2) are nuclear receptors belonging to the superfamily of ligand-activated transcription factors with a key role in the control of lipid and glucose metabolism. Studies of the phenotype of LXRalpha-/-mice and LXRbeta-/-mice have shown that these nuclear receptors have specific and distinct roles, although they share very high sequence homology (78%). READ MORE

  6. 24. Lifestyle risk factors for Parkinson disease and amyotrophic lateral sclerosis : an epidemiological perspective

    Author : Elin Roos; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Following progressive aging of the population, the global prevalence of PD and ALS is expected to increase in the next decades. Primary prevention of the diseases is hampered by limited knowledge of preventable causes. READ MORE

  7. 25. Cholinergic mechanisms in the spinal cord : topographical localizations of choline acetyltransferase and neuroreceptors and their changes in amyotrophic lateral sclerosis

    Author : Per-Göran Gillberg; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE