Search for dissertations about: "analogs"

Showing result 1 - 5 of 151 swedish dissertations containing the word analogs.

  1. 1. Carbohydrate-Based Inhibitors of Pathogen Adhesion to Cell Surface Glycoconjugates

    Author : Henrik C Hansen; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Galabiose analogs; Globotriose analogs; Escherichia coli; verotoxin; PapG adhesion; Streptococcus suis; Dendrimers; Multivalency; Amino-deoxy analogs; Organic chemistry; Inhibitor; Ceramide analogs; Glycoconjugates; Organisk kemi;

    Abstract : The fact that a growing number of pathogens develop resistance against traditional treatment is a growing medical problem. Infections, which until now have been harmless, might turn into life threatening diseases. These problems have led to an intensified search for alternative treatments. Analogs of cell surface glycoconjugates are an alternative. READ MORE

  2. 2. Synthetic analogs of sialyl Lewis x

    Author : Ulf Ellervik; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; stereoselective synthesis; regioselective synthesis; lactam analogs; lactone; Selectin; Sialyl Lewis x; SLex; Organic chemistry; Organisk kemi;

    Abstract : The sialyl Lewis x (SLex) tetrasaccharide is the smallest recognizable ligand for selectins. The selectins constitute a vital part of the inflammatory cascade for recruitment of leukocytes to a site of tissue damage or microbial infection. READ MORE

  3. 3. Bioactive Compounds from the Marine Sponge Geodia barretti : Characterization, Antifouling Activity and Molecular Targets

    Author : Martin Sjögren; Lars Bohlin; Per Jonsson; Anna-Karin Borg-Karlsson; Uppsala universitet; []
    Keywords : Pharmacognosy; Geodia barretti; barettin; secondary metabolites; settling inhibition; Balanus improvisus; analogs; 5-HT; Farmakognosi;

    Abstract : The marine sponge Geodia barretti produces a range of secondary metabolites. Two of these compounds were isolated and elucidated guided by their ability to inhibit settlement of cypris larvae of the barnacle Balanus improvisus. READ MORE

  4. 4. Galanin and neuropeptide Y analogs : receptor-ligand interactions and pharmacology

    Author : Ulrika Kahl; Dan Larhammar; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurochemistry; Neurokemi; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Abstract : .... READ MORE

  5. 5. Lowcoordinated Silicon and Hypercoordinated Carbon : Structure and Stability of Silicon Analogs of Alkenes and Carbon Analogs of Silicates

    Author : Anders M. Eklöf; Henrik Ottosson; Sten Lunell; Thomas Müller; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; silenes; zwitterionic silenes; silenolates; reverse polarization; natural resonance theory; hypervalent carbon; hypercoordinated carbon; thermolysis; lowcoordinated silicon; Organic chemistry; Organisk kemi;

    Abstract : Quantum chemical studies on lowcoordinated group 14-16 compounds have been performed. This thesis focuses particularly on silenes influenced by reverse Siδ-=Cδ+ bond polarization. Hypercoordinated carbon compounds are also studied. READ MORE