Search for dissertations about: "analogue modeling"

Showing result 1 - 5 of 13 swedish dissertations containing the words analogue modeling.

  2. 1. Preclinical tumor-immune modeling : For the identification of immunomodulatory drugs

    Author : Tove Selvin; Mårten Fryknäs; Rolf Larsson; Claes Andersson; Malin Jarvius; Brinton Seashore-Ludlow; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immuno-oncology; anti-cancer drugs; preclinical modeling; drug screening; repurposing;

    Abstract : For a long time, the field of cancer research was dominated by a tumor cell-centric view. That, however, changed once it became recognized that medical cancer treatment is largely influenced by the combined effect exerted on both cancer and immune cells. READ MORE

  4. 2. Kinematics and Internal Deformation of Granular Slopes

    Author : Zhina Liu; Hemin Koyi; Dominique Frizon de Lamotte; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; granular flow; kinematics; internal deformation; particle flow method; analogue modeling; natural landslides; Geovetenskap med inriktning mot mineralogi; petrologi och tektonik; Earth Science with specialization in Mineral Chemistry; Petrology and Tectonics;

    Abstract : Flow-like mass movement is the most destructive landslide and causes loss of lives and substantial property damage throughout the world every year. This thesis focuses on the spatial and temporal changes of the mass movement in terms of velocity and displacement within the failure mass, and the spatial and temporal distribution of the three dimensional internal deformation of the granular slopes using discrete element method, physical experiments, and natural landslides. READ MORE

  5. 3. Physiology of Saccharomyces cerevisiae Producing Recombinant Insulin in Continuous Culture

    Author : Ali Kazemi Seresht; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; unfolded protein response; Keywords: heterologous protein production; prolonged chemostat; transcriptome; insulin analogue precursor; metabolic adaptation; URA3d; plasmid copy number; promoter truncation; high cell density cultivation; TPI1;

    Abstract : The yeast Saccharomyces cerevisiae has widely been used as a host for the production of heterologous proteins. High-level production of heterologous proteins is likely to impose a metabolic burden on the host cell and can thus affect various aspects of cellular physiology. READ MORE

  6. 4. Biomechanical analyses of flywheel resistance exercise : From a space- and ground-based perspective

    Author : Maria Sjöberg; Ola Eiken; Elena Gutierrez-Farewik; Hans E Berg; Patrik Sundblad; Loren FZ Chiu; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; AnyBody Modeling System; concentric; eccentric; eccentric overload; inverse dynamics; knee extensors; microgravity; musculoskeletal deconditioning; net-joint moment; AnyBody Modeling System; excentrisk; excentrisk överbelastning; invers dynamik; knäextensorer; koncentrisk; ledmoment; mikrogravitation; muskuloskeletal nedbrytning; Teknik och hälsa; Technology and Health;

    Abstract : Astronauts suffer degradation of postural muscles and weight-bearing bones during long-duration spaceflight. Resistance exercise is used as a primary countermeasure against these degradations. READ MORE

  7. 5. Tectonic History and Present-Day Deformation in the Zagros Fold-Thrust Belt

    Author : Khaled Hessami; James Jackson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Earth sciences; Zagros; Orogeny; Unconformities; Iran; Growth folds; Middel East; Tectonics; Models; GPS; basement; Seismicity; Geovetenskap; Earth sciences; Geovetenskap; mineralogi; petrologi och tektonik; Mineral Chemistry; Petrology and Tectonics;

    Abstract : This thesis uses various approaches such as observation of satellite images, field investigations, analogue modeling and GPS measurements to constrain deformation of the basement and sedimentary cover of the Zagros fold-thrust belt in time and space.Focal mechanism solutions of most earthquakes indicate that deformation in the Zagros basement is due to shortening and thickening through numerous thrust faults. READ MORE