Search for dissertations about: "ancestral reconstruction"
Showing result 1 - 5 of 23 swedish dissertations containing the words ancestral reconstruction.
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1. Engineering enzymes towards biotherapeutic applications using ancestral sequence reconstruction
Abstract : Enzymes are versatile biocatalysts that fulfill essential functions in all forms of life and, therefore, play an important role in health and disease. One specific application of enzymes in life science is their use as biopharmaceuticals, which typically benefits from high catalytic activity and stability. READ MORE
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2. Computational problems in evolution : Multiple alignment, genome rearrangements, and tree reconstruction
Abstract : Reconstructing the evolutionary history of a set of species is a fundamental problem in biology. This thesis concerns computational problems that arise in different settings and stages of phylogenetic tree reconstruction, but also in other contexts. READ MORE
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3. The Dawn of a New Age : Interrelationships of Acoela and Nemertodermatida and the Early Evolution of Bilateria
Abstract : Deciphering the rapid emergence of bilaterian animals around the time of the Cambrian Explosion and reconstructing the interrelationships of animal groups have long been two of the most elusive problems in Zoology. This thesis concerns the phylogenetic interrelationships within and among Acoela and Nemertodermatida, two groups of small worms that are believed to be basal bilaterians and which may provide important clues for understanding the early evolution of animals. READ MORE
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4. Genomic and evolutionary exploration of Asgard archaea
Abstract : Current evolutionary theories postulate that eukaryotes emerged from the symbiosis of an archaeal host with, at least, one bacterial symbiont. However, our limited grasp of microbial diversity hampers insights into the features of the prokaryotic ancestors of eukaryotes. READ MORE
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5. In silico protein design for the enhancement of protein stability and function
Abstract : Enzymes are natures catalysts that increase the rate of a chemical reaction. The increased rate of a reaction is required to be able to sustain life. Despite the huge impact of enzymes, they are not perfect catalysts. READ MORE