Search for dissertations about: "androgen excess"

Showing result 1 - 5 of 10 swedish dissertations containing the words androgen excess.

  2. 1. Polycystic ovary syndrome – Studies of metabolic and ovarian disturbances and effects of physical exercise and electro-acupuncture

    Author : Louise Mannerås Holm; Göteborgs universitet; []
    Keywords : adipocyte size; adipose tissue; androgen excess; animal models; body composition; electro-acupuncture; insulin resistance; ovary; physical exercise; polycystic ovary syndrome;

    Abstract : Polycystic ovary syndrome (PCOS) is the most common endocrine abnormality in premenopausal women. The syndrome is characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovarian (PCO) morphology. Metabolic disturbances, such as insulin resistance and obesity, are also associated with PCOS. READ MORE

  4. 2. Studies of androgen receptor gene mutations in patients phenotypically ranging from complete androgen insensitivity to men with preserved fertility

    Author : Yvonne Lundberg Giwercman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : androgen insensitivity; androgen receptor; mutations; genetic diagnostics; abnormal sex differentiation; infertility;

    Abstract : The androgen insensitivity syndrome (AIS) is the single most common cause of male pseudohermaphroditism, i. e., deficient masculinization which is not explained by disturbed testis development. In its most severe form it affects at least 1/20 000 newborn 46, XY males. READ MORE

  5. 3. Single-cell transcriptomic analyses of early embryonic development and developmental programming by androgen excess

    Author : Yu Pei; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Infertility is a compelling problem an increased prevalence among couples. Although multiple causes have been hypothesized to increase the risk of infertility, changes in lifestyles and environment are the possible links to the causes. READ MORE

  6. 4. Developmental origins of polycystic ovary syndrome : role of early adverse life events on adult health

    Author : Maria Manti; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The research focus of this thesis is polycystic ovary syndrome (PCOS), the most common endocrine disorder among women of reproductive age, associated with reproductive, cardio-metabolic, and mental health complications. Despite the high prevalence, little is known about the etiology of the syndrome. READ MORE

  7. 5. Metabolic and cognitive effects after early prenatal dexamethasone treatment

    Author : Lena Wallensteen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Congenital adrenal hyperplasia (CAH), due to 21-hydroxylase deficiency (21OHD), is a disease with an inborn error of the adrenal steroid synthesis. This enzyme deficiency leads to cortisol shortage and androgen excess. READ MORE