Search for dissertations about: "angiogenesis"

Showing result 16 - 20 of 400 swedish dissertations containing the word angiogenesis.

  2. 16. On the stimulatory effect of microglial cells on angiogenesis

    Author : Simin Rymo; Göteborgs universitet; []
    Keywords : microglia; angiogenesis; aortic ring;

    Abstract : ABSTRACT Angiogenesis, the process by which new vessels sprout from pre-existing vessels, is fundamental to development, tissue growth and repair. The main aim of this thesis was to investigate the role of microglia on angiogenesis. We adapted the rat ex vivo/in vitro aortic ring model to the mouse in a 3-D culture system. READ MORE

  4. 17. Regulation of VEGFR2 signaling in angiogenesis and vascular permeability

    Author : Chiara Testini; Lena Claesson-Welsh; Mats Hellström; Mauro Giacca; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; VEGFR2; angiogenesis; permeability; NRP1; Y949; Y1212; paladin; Molekylär medicin; Molecular Medicine;

    Abstract : Angiogenesis and vascular permeability occur in physiological and pathological conditions. Angiogenesis denotes the process of blood vessel formation from preexisting quiescent vessels. READ MORE

  5. 18. Androgen-Independent Prostate Cancer - studies on angiogenesis and ADAMTS1

    Author : Helene Gustavsson; Göteborgs universitet; []
    Keywords : Prostate cancer; Androgen-independent; Castration resistant; Hormone refractory; Angiogenesis; Microvessel density; ADAMTS1; LNCaP; VEGF; TSP1;

    Abstract : Androgen deprivation therapy (ADT) is the standard treatment for advanced prostate cancer since prostate tumors initially are dependent on androgens for growth. However, most tumors will eventually relapse and grow in a highly aggressive and androgen-independent (AI) manner. READ MORE

  6. 19. Therapeutic Cancer Vaccines Targeting Molecules Associated with Tumor Angiogenesis

    Author : Julia Femel; Anna-Karin Olsson; Grietje (Ingrid) Molema; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tumor; therapeutic; cancer vaccine; angiogenesis; vasculature; fibronectin; galectin-1; Medical Cell Biology; Medicinsk cellbiologi; Oncology; Onkologi; Biomedicinsk laboratorievetenskap; Biomedical Laboratory Science; Medical Science; Medicinsk vetenskap;

    Abstract : Induction of an endogenous antibody response by therapeutic vaccination could provide an alternative to cost-intensive monoclonal antibody-based treatments for cancer. Since the target of a cancer vaccine will most likely be a self-antigen, self-tolerance of the immune system must be circumvented. READ MORE

  7. 20. Angiogenesis Related Markers In Non-Small Cell Lung Cancer

    Author : Daniel Brattström; Ola Brodin; Gunnar Wagenius; Torgny Rasmusen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Lung cancer; NSCLC; Therapy; Angiogenesis; VEGF; bFGF; Microvessel density; Survival; Onkologi; Oncology; Onkologi;

    Abstract : This thesis investigated the predictive and the prognostic powers of angiogenesis related markers in both operable and inoperable non-small cell lung cancer (NSCLC) patients.In the first and second study, we investigated the serological fractions of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in 2 cohorts of patients with either operable or inoperable NSCLC. READ MORE