Search for dissertations about: "angiotensin ii receptor antagonism"
Showing result 1 - 5 of 7 swedish dissertations containing the words angiotensin ii receptor antagonism.
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1. Cardiovascular risk factors in renal artery stenosis : Effects of renal angioplasty and angiotensin II receptor antagonism
Abstract : Renovascular hypertension (RVH) caused by atherosclerotic renal artery stenosis (ARAS) is one of the most common forms of secondary hypertension. The prognosis for patients with RVH is much worse compared to patients with primary hypertension, and caused by a high cardiovascular morbidity. READ MORE
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2. Renal hemodynamics in renal artery stenosis and angiotensin II-dependent hypertension. Pathophysiological and diagnostic aspects
Abstract : Patients with renovascular hypertension have a poor renal and cardiovascular prognosis. To improve the care of these patients, we need to increase knowledge about the pathophysiological mechanisms involved. READ MORE
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3. Design, Synthesis and Biological Evaluation of Selective Nonpeptide AT2 Receptor Agonists and Antagonists
Abstract : The G protein-coupled receptors (GPCRs) are important targets in drug discovery. In several cases, the endogenous ligands that activate the GPCRs of pharmaceutical interest are peptides. READ MORE
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4. Vascular mechanisms in ovulation
Abstract : Ovulation is a unique biological process, which involves the degradation and rupture of healthy tissue of the ovarian follicle and the extrusion of the oocyte. This process is initiated by the preovulatory surge of luteinizing hormone (LH), which leads to the up-regulation of various intraovarian mediators. READ MORE
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5. Effects of the angiotensin II type 1 receptor blocker (AT₁ receptor blocker) candesartan cilexetil on systemic and renal haemodynamics in hypertensive patients
Abstract : Established primary hypertension is primarily characterised by elevated peripheral resistance and an increase in renal vascular resistance. Antagonism of angiotensin II may be a particularly relevant intervention in this condition, as angiotensin II is known to act both as a powerful vasoconstrictor and as a stimulus to vascular hyperthrophy. READ MORE