Search for dissertations about: "angiotensin receptor blockers"

Showing result 6 - 10 of 23 swedish dissertations containing the words angiotensin receptor blockers.

2. 6. Mortality in Oxygen-Dependent Chronic Obstructive Pulmonary Disease and Possibilities for Pharmacological Interventions

   Author : Magnus Ekström; allergologi och palliativ medicin Lungmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; COPD; mortality; survival; comorbidity; cardiovascular disease; cardiovascular drugs; angiotensin-converting enzyme inhibitor; angiotensin receptor blocker; beta blocker; statin; aspirin; antiplatelet drug; gender; sex; oxygen-dependent; LTOT; trends; excess mortality; SMR; hypoxemia; hypoxia; hypoxaemic;

   Abstract : Background Chronic obstructive pulmonary disease (COPD) is a major and rising cause of mortality worldwide, especially in women. Patients with chronic hypoxia owing to COPD are treated with long-term oxygen therapy (LTOT) but have high morbidity and mortality. READ MORE

4. 7. Effects of the angiotensin II type 1 receptor blocker (AT₁ receptor blocker) candesartan cilexetil on systemic and renal haemodynamics in hypertensive patients

   Author : Katarina Fridman; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Established primary hypertension is primarily characterised by elevated peripheral resistance and an increase in renal vascular resistance. Antagonism of angiotensin II may be a particularly relevant intervention in this condition, as angiotensin II is known to act both as a powerful vasoconstrictor and as a stimulus to vascular hyperthrophy. READ MORE

5. 8. Computational prediction of ligand binding in peptide G-protein coupled receptors

   Author : Silvana Vasile; Hugo Gutiérrez-de-Terán; Johan Åqvist; Herman Van Vlijmen; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; GPCR; neuropeptide Y; angiotensin II receptor; molecular dynamics; free energy perturbation; homology modelling; computer simulations; peptide binding; peptidomimetics; binding free energy.;

   Abstract : G-protein coupled receptors (GPCRs) are a superfamily of membrane receptors involved in a wide variety of biological processes, and their malfunction is associated with many diseases. Consequently, GPCRs are targeted by one-third of the drugs on the market, and constitute the focus of active public and private research in the search of more effective drugs. READ MORE

6. 9. Angiotensin converting enzyme inhibition and aspirin in congestive heart failure

   Author : Tord Juhlin; Kardiologiska klinikens forskargrupp; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; clinical trial; ARBs; renal function; congestive heart failure; ischaemic heart disease; NSAIDs; ACE-inhibitors; aspirin; dose dependency; Cardiovascular system; Kardiovaskulära systemet;

   Abstract : Angiotensin-converting enzyme (ACE) inhibitors act by decreasing production of angiotensin II and by potentiating the effects of bradykinin by inhibition of its breakdown. Bradykinin exerts part of its effects via vasodilating prostaglandins. Since the cyclooxygenase (COX)-inhibitors, e.g. READ MORE

7. 10. Hypertension, atherosclerosis and fracture risk - observational investigations with focus on antihypertensive therapy

   Author : Tove Bokrantz; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epidemiology; hypertension; antihypertensive agents; fractures; peripheral arterial disease; bone density;

   Abstract : Aim: To investigate associations between hypertension, arteriosclerotic disease, and fracture risk in adults and the elderly, with a certain focus on how specific antihypertensive drug treatments in patients with high blood pressure might affect the risk for fractures. Methods and results: In Study I and II, the associations between different antihypertensive treatments and fracture risk were investigated in a cohort of about 60. READ MORE