Search for dissertations about: "angiotensin-converting enzyme inhibitor"

Showing result 11 - 13 of 13 swedish dissertations containing the words angiotensin-converting enzyme inhibitor.

  1. 11. Impairment of Endothelial Thromboprotective Function by Haemodynamic and Inflammatory Stress - Implications for hypertensive disease

    Author : Erik Ulfhammer; Göteborgs universitet; []
    Keywords : tissue-type plasminogen activator; endothelium; fibrinolysis; hypertension; shear stress; strain; antihypertensive agents; inflammation; TNF-alpha; NF-kappaB; MAPK;

    Abstract : The physiologically most important activator of intravascular fibrinolysis is tissue-type plasminogen activator (t-PA). The endothelium synthesizes and stores t-PA and regulated release of the enzyme is an important local protective response to prevent thrombus extension. READ MORE

  2. 12. Vascular and endothelial function in human hypertension, and the importance of the renin-angiotensin-aldosterone system

    Author : Andreas Jekell; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Hypertension induces structural vascular and cardiac changes with increased arterial stiffness and left ventricular (LV) hypertrophy and is major risk factor for cardiovascular morbidity and mortality. The renin-angiotensin-aldosterone system (RAAS) and the sympathetic nervous system are important for blood pressure regulation and vascular function. READ MORE

  3. 13. Identification of genes and pathways involved in the development and progression of glomerular diseases

    Author : Dina Dabaghie; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Chronic kidney disease (CKD) affects millions of people worldwide and is characterized by a reduction in glomerular filtration rate and albuminuria resulting in a gradual loss of kidney function. The high prevalence of the disease, along with the limited treatment options available, makes it a major burden to the health care systems around the world. READ MORE