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Showing result 1 - 5 of 10 swedish dissertations matching the above criteria.

  2. 1. Maternal deprivation and mood stabilizing drugs : effects on rat brain NPY

    Author : Henriette Husum Bak-Jensen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Maternal deprivation; stress; mood stabilizing drugs; NPY; mood disorders; depression; anhedonia; Hinders Sensitive Line rats; Amygdala-kindling; microdialysis; RIA; histochemistry.;

    Abstract : Experiences of early adverse life events are more frequent among adult depressed patients than healthy subjects. Studies with non-human primates and rats show that maternal deprivation leads to changes in hypothalamic-pituitary adrenal (HPA)-axis activity/reactivity and increased levels of anxiety and alcohol preference. READ MORE

  4. 2. Paranormal Beliefs and Experiences in Relation to Subjective Health and Schizotypy

    Author : Anneli Goulding; Göteborgs universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

    Abstract : This thesis aimed at investigating paranormal beliefs and experiences in relation to subjective health and ill-health in terms of schizotypy. Following a literature review, two empirical studies are presented. The purpose of the studies was to investigate which of two models best describes the construct schizotypy. READ MORE

  5. 3. Negative symptoms, repetitive transcranial magnetic stimulation and heart rate variability in schizophrenia and depression

    Author : Johan Bengtsson; Robert Bodén; Jonas Persson; Erik Olsson; Caroline Wass; Jimmi Nielsen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; negative symptoms; psychotic disorders; affective disorders; non-invasive brain stimulation; transdiagnostics; psychometrics; autonomic nervous system; Psychiatry; Psykiatri;

    Abstract : Negative symptoms comprise anhedonia, avolition, and blunted affect. Although first described in schizophrenia, these symptoms share phenomenology with the depressive state. Pharmacological treatment has not been successful in reducing negative symptoms. READ MORE

  6. 4. Self-rated health : biobehavioral determinants with focus on inflammatory factors

    Author : Anna Nixon Andreasson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Self-rated (subjective) health is an independent predictor of future mortality, but neither the mechanisms behind this relation nor the biological determinants of poor self-rated health are known. Inflammatory cytokines give rise to a sickness response which includes fatigue, malaise, anhedonia and pain, resembling factors that are known to impact negatively on self-rated health. READ MORE

  7. 5. Finding improved drug strategies for schizophrenia : Preclinical studies on lumateperone and sodium nitroprusside

    Author : Joep Titulaer; Åsa Konradsson-Geuken; Anne-Lie Svensson; Erika Roman; Kent Jardemark; Joshua Beckmann; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; schizophrenia; lumateperone; sodium nitroprusside; antipsychotic drugs; Farmaceutisk vetenskap; Pharmaceutical Science; Pharmacology; Farmakologi; Psychiatry; Psykiatri;

    Abstract : Schizophrenia is a severe psychiatric disorder affecting approximately 20 million people worldwide. The disease consists of positive symptoms e.g. hallucinations, negative symptoms such as anhedonia, and cognitive deficits, e. READ MORE