Search for dissertations about: "animal model in medicine"

Showing result 1 - 5 of 404 swedish dissertations containing the words animal model in medicine.

  2. 1. Uridine, 4-thiouridine and isomaltitol in an asthma-like model : Anti-inflammatory and modulating effects

    Author : Chamilly Evaldsson; Srinivas Uppugunduri; Margareta Linden; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Uridine; asthma; 4-thiouridine; isomaltitol; isomalt; inflammation; eosinophilia; Sephadex; animal model; rat; Pharmaceutical pharmacology; Farmaceutisk farmakologi; MEDICINE; MEDICIN; Lung diseases; Lungsjukdomar;

    Abstract : In chronic inflammatory diseases like asthma or rheumatoid arthritis, erroneous and exaggerated accumulation of leukocytes in a tissue inadvertently causes the body harm. Several efficient anti-inflammatory drugs exist, for example corticosteroids and cyclo-oxygenase inhibitors. READ MORE

  4. 2. Ovarian steroids in rat and human brain : effects of different endocrine states

    Author : Marie Bixo; Bengt Winblad; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Progesterone; 5a-pregnane-3.20-dione; estradiol; testosterone; rat brain; human brain; PMSG-model; steroid anaesthesia;

    Abstract : Ovarian steroid hormones are known to produce several different effects in the brain. In addition to their role in gonadotropin release, ovulation and sexual behaviour they also seem to affect mood and emotions, as shown in women with the premenstrual tension syndrome. Some steroids have the ability to affect brain excitability. READ MORE

  5. 3. Novel Treatment Modalities for High-Risk Neuroblastoma : Studies in Animal Models

    Author : Dieter Fuchs; Faranak Azarbayjani; Rolf Christofferson; Sven Påhlman; Uppsala universitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; neuroblastoma; bevacizumab; SU11248; GMX1778; GMX1777; animal model; Medicine; Medicin;

    Abstract : Neuroblastoma, the most common extracranial solid tumor of childhood, is a heterogeneous tumor. In some patients, the tumor can go into spontaneous regression and disappear whereas other patients have rapidly growing tumors with a poor prognosis. READ MORE

  6. 4. Regional Lung Mechanics and Influence of an Active Diaphragm in Experimental Lung Injury

    Author : Mariangela Pellegrini; Anders Sune Larsson; Göran Hedenstierna; Michael Quintel; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute respiratory distress syndrome; artificial respiration; diaphragm; pulmonary atelectasis; lung imaging; respiratory system; animal model; Fysiologi; Physiology; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Abstract : Despite being an essential life-support strategy in severe respiratory failure, mechanical ventilation can, if not optimally set and monitored, lead to injury of the lung parenchyma and diaphragm. These conditions are called ventilator-induced lung injury and ventilator-induced diaphragmatic dysfunction (VIDD), respectively. READ MORE

  7. 5. Modulating Organ Dysfunction in Experimental Septic Shock : Effects of Aminoglycosides, Antiendotoxin Measures and Endotoxin Tolerance

    Author : Markus Castegren; Jan Sjölin; Claes Frostell; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipopolysaccharide; animal model; pig; tobramycin; endotoxin elimination; immunoparalysis; secondary sepsis; Infectious diseases; Infektionssjukdomar; Infektionssjukdomar; Infectious Diseases;

    Abstract : Sepsis is a common diagnose in the intensive care population, burdened with a high mortality. The systemic inflammatory reaction underlying the development of septic organ dysfunction can be modeled using Gram-negative bacterial lipopolysaccharide, endotoxin. READ MORE