Search for dissertations about: "anti bias"

Showing result 1 - 5 of 33 swedish dissertations containing the words anti bias.

  2. 1. Biological Aspects of Peripartum Depression

    Author : Åsa Edvinsson; Inger Sundström Poromaa; Helena Åkerud; Jocelien Olivier; Charlotte Hellgren; Isis Amer-Wåhlin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peripartum depression; antenatal depression; postpartum depression; antidepressant treatment; selective serotonin reuptake inhibitor; SSRI; pregnancy; postpartum; attentional bias; Emotional Stroop Task; inflammatory markers; proximity extension assay; placenta; gene expression; TaqMan low-density array; protein expression; immunohistochemistry; HTR1A; NPY2R;

    Abstract : Peripartum depression affects around 12% of women in pregnancy and postpartum, and about 2–3% of European pregnant women use antidepressants, mostly selective serotonin reuptake inhibitors (SSRIs). An increased risk of poor pregnancy outcomes has been described in women with antenatal depression and SSRI treatment during pregnancy. READ MORE

  4. 2. Old receptors learn new tricks : biasing anti-IGF1R cancer therapy through the GPCR system

    Author : Dawei Song; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : As cancers progress, tumor cells exploit the extracellular signals generated from plasma membrane receptors for cell growth, migration, and anti-apoptosis. G protein-coupled receptors (GPCR) and receptor tyrosine kinases (RTKs) are two important families of plasm membrane receptors, controlling multiple biological functions via their downstream signaling. READ MORE

  5. 3. Pharmacokinetic-Pharmacodynamic Evaluations and Experimental Design Recommendations for Preclinical Studies of Anti-tuberculosis Drugs

    Author : Chunli Chen; Ulrika Simonsson; Mats Karlsson; Sebastian Wicha; Bernd Meibohm; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tuberculosis; pharmacokinetics; pharmacodynamics; pharmacometrics; the Multistate Tuberculosis Pharmacometric model; the General Pharmacodynamic Interaction model; optimized design; rifampicin; isoniazid; ethambutol; pyrazinamide; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : Tuberculosis is an ancient infectious disease and a leading cause of death globally. Preclinical research is important for defining drugs and regimens which should be carried forward to human studies. READ MORE

  6. 4. Anti-citrulline immunity in rheumatoid arthritis : characterization of peptide-HLA interactions and CD4+ T cell responses

    Author : Christina Gerstner; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rheumatoid Arthritis (RA) is a complex, systemic autoimmune disorder characterized by chronic inflammation in small joints in hands and feet. It is a common disease that if untreated leads to joint destruction, disability, comorbidities and a reduced lifespan. READ MORE

  7. 5. Factors associated with brain tumor risk : with focus on female sex hormones and allergic conditions

    Author : Annette Wigertz; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Glioma; meningioma; case-control study; contraceptives; hormone replacement therapy; allergy; pregnancy; participation; selection bias;

    Abstract : Every year approximately 1200 people in Sweden are diagnosed with a brain tumor. The two main histological types of brain tumors, gliomas and meningiomas, differ in terms of their localization, histology, prognosis, and probably etiology. READ MORE