Search for dissertations about: "anti cerebral Stroke"

Showing result 1 - 5 of 9 swedish dissertations containing the words anti cerebral Stroke.

2. 1. Role of classical pro- and anti-inflammatory mediators in ischemic stroke. Beyond neuroimmunomodulation

   Author : Ana Inacio; Sektion IV; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; interferon-β; inflammatory immune cells; galectin-3; experimental stroke; enriched environment; cytokines; Brain; macrophage migration inhibitory factor; neuroprotection; reactive astrocytes.;

   Abstract : Stroke is a leading cause of death and long-term neurological deficits worldwide, and no effective treatment is available for the vast majority of the stroke patients. A rapid and persistent activation of multiple and dynamic inflammatory and immune cascades, in and outside the brain, occurs after stroke. READ MORE

4. 2. Apoptotic and necrotic cell death after photothrombotic ring stroke : characterization of a stroke model and its morphological and molecular consequences

   Author : Xiao-Lei Hu; Per Wester; Klas Blomgren; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Cerebral ischemic cell death is a major cause of disability and death among stroke patients. The brain cell demise can occur through apoptosis or necrosis or as a continuum of both. This study aimed at establishing a dual setup of a photothrombotic ring stroke model and exploring its morphological and molecular consequences. READ MORE

5. 3. The role of the alpha 7 nicotinic acetylcholine receptor in inflammation and brain injury

   Author : Maria Hammarlund; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alpha 7 nicotinic acetylcholine receptor; inflammation; brain injury; CHRNA7; CHRFAM7A; stroke; hypoxia ischemia; neonatal encephalopathy; human; PBMC;

   Abstract : The alpha 7 nicotinic acetylcholine receptors (α7nAChR) are expressed in the nervous system as well as on peripheral immune cells where it participates in the cholinergic anti-inflammatory pathway. Inflammation is a common component in the pathology of many diseases and injuries, including brain damage. READ MORE

6. 4. Blood pressure in acute ischaemic stroke : blood pressure and stress in the acute phase of stroke and influence of initial blood pressure on stroke-outcome

   Author : Niaz Ahmed; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Stroke; cerebral ischaemia; cerebral infarction; brain infarction; cerebrovascular disorder; blood pressure; hypertension; stroke classification; stroke subtypes; clinical trials; stress; cortisol; glucocorticoid; nimodipine; Calcium channel blockers; outcome; OCSP; RCT;

   Abstract : Background and objectives: Most patients (70-80%) with acute ischaemic or haemorrhagic stroke exhibit a high systemic blood pressure (BP) on admission to hospital even in the absence of a history of hypertension (=50%). In matched-control patients admitted to hospital for other acute diseases the proportion of high BP is only 36%. READ MORE

7. 5. Studies on cytokines and chemokines in cerebrovascular diseases and experimental cerebral ischemia

   Author : Nikolaos Kostulas; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Ischemic brain injury secondary to arterial occlusion, a major cause of stroke, is characterized by acute local inflammation, which involves the accumulation of polymorphonuclear neutrophils and other immune cells. Tissue damage resulting from ischemic stroke can be reduced in experimental animal models by blocking leukocyte accumulation. READ MORE