Search for dissertations about: "anti diabetic activity"
Showing result 1 - 5 of 22 swedish dissertations containing the words anti diabetic activity.
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1. Anti-Diabetic and Beta-Cell Protective Actions of Imatinib Mesylate
Abstract : Type 1 diabetes is a disease resulting from the progressive immune-mediated destruction of insulin producing β-cells. In order to understand more about diabetes we need to understand the mechanisms governing β-cell death.The leukemia drug Gleevec is a tyrosine kinase inhibitor that targets c-Abl. READ MORE
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2. Anti-diabetic effect of gynostemma pentaphyllum tea in type 2 diabetes
Abstract : Type 2 diabetes mellitus (T2D) is a major non-communicable disease and an important health burden worldwide, especially in the developing countries including Vietnam. Gynostemma pentaphyllum has been widely used in Vietnam as a herbal medicine for the prevention and treatment of T2D but the mechanism related to its effects is unknown. READ MORE
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3. Macro- and microvascular complications of diabetes: Studies on NFAT (Nuclear Factor of Activated T-cells) as a novel target for the treatment of atherosclerosis and vascular dysfunction in diabetes
Abstract : Diabetes is associated with devastating chronic complications including coronary heart disease and stroke (macrovascular complications) as well as microvascular disorders leading to damage of the small vessels and the development of retinopathy, nephropathy and neuropathy. The underlying pathogenesis is not clear, but hyperglycemia has been identified as an important risk factor. READ MORE
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4. NK cell recognition : adaptability to host factors in normal and diabetic mice
Abstract : The overall aim of this thesis was to understand the rules, which guide NK cell behavior in vivo. NK cells are part of the innate immune system and are important in defense against certain virus infections and tumorigenic cells. They also play a role in rejecting bone marrow grafts. READ MORE
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5. Studies on factors modulating glucose homeostasis in healthy and diabetic rats
Abstract : Glucose is the most common substrate for energy metabolism. Despite the varying demands for glucose, the body needs to regulate its internal environment and maintain a constant and stable condition. Glucose homeostasis requires harmonized interaction between several tissues, achieving equilibrium between glucose output and uptake. READ MORE