Search for dissertations about: "anti inflammatory thesis"

Showing result 1 - 5 of 855 swedish dissertations containing the words anti inflammatory thesis.

2. 1. Uridine, 4-thiouridine and isomaltitol in an asthma-like model : Anti-inflammatory and modulating effects

   Author : Chamilly Evaldsson; Srinivas Uppugunduri; Margareta Linden; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Uridine; asthma; 4-thiouridine; isomaltitol; isomalt; inflammation; eosinophilia; Sephadex; animal model; rat; Pharmaceutical pharmacology; Farmaceutisk farmakologi; MEDICINE; MEDICIN; Lung diseases; Lungsjukdomar;

   Abstract : In chronic inflammatory diseases like asthma or rheumatoid arthritis, erroneous and exaggerated accumulation of leukocytes in a tissue inadvertently causes the body harm. Several efficient anti-inflammatory drugs exist, for example corticosteroids and cyclo-oxygenase inhibitors. READ MORE

4. 2. Immunopathology of Inflammatory Bowel Disease

   Author : Mohammad Kadivar; Leukocyt migration; []
   Keywords : Inflammatory bowel disease IBD ; Crohn s disease; Ulcerative colitis; T cell; Monocyte; macrophage; Neutrophil; anti-TNFa treatment; IBD disease activity index;

   Abstract : Inflammatory bowel disease (IBD) is a chronic inflammatory condition affecting the gastrointestinal tract, with a remitting and relapsing course. There are two main forms of IBD: Crohn’s disease (CD) and ulcerative colitis (UC). READ MORE

5. 3. Molecular mechanisms of glucocorticoids : anti-inflammatory implications

   Author : Krishan Johansson-Haque; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Glucocorticoids (GCs) play important roles in many biological processes including inflammatory responses. The study of this process has involved investigations of cross-talk abilities by GC receptor (GR) with cellular signaling pathways that have been associated with inflammatory disorders or implicated as contributory for the adverse effects observed with GC therapy. READ MORE

6. 4. Non-Steroidal Anti-Inflammatory Drugs in Cyclooxygenases 1 and 2 : Binding modes and mechanisms from computational methods and free energy calculations

   Author : Yasmin Shamsudin Khan; Johan Åqvist; Hugo Gutiérrez de Terán; Xavier Barril; Uppsala universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; molecular dynamics simulations; binding free energy; molecular docking; cyclooxygenase; non-steroidal anti-inflammatory drugs; free energy perturbation; potentials of mean force;

   Abstract : Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly used classes of drugs. They target the cyclooxygenases (COX) 1 and 2 to reduce the physiological responses of pain, fever, and inflammation. Due to their role in inducing angiogenesis, COX proteins have also been identified as targets in cancer therapies. READ MORE

7. 5. Clinical aspects of biological treatment in inflammatory bowel disease

   Author : Sara Karlqvist; Jonas Halfvarson; Carl Eriksson; Scott Montgomery; Michael Sachs; Julien Kirchgesner; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ulcerative colitis; Crohn’s disease; anti-TNF; vedolizumab; comparative effectiveness; serious infections; inflammatory bowel disease; clinical aspects; register-based studies;

   Abstract : Inflammatory bowel disease (IBD) including its main subtypes, Crohn’s disease and ulcerative colitis, is a chronic and recurrent inflammatory condition that affects the entire gastrointestinal system. Biological treatment has revolutionized the therapeutic armamentarium in the past two decades. READ MORE