Search for dissertations about: "anti smoking"

Showing result 11 - 15 of 77 swedish dissertations containing the words anti smoking.

  2. 11. Cigarette smoking and silica exposure as determinants for the development of rheumatoid arthritis

    Author : Patrik Stolt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rheumatoid arthritis (RA) is an autoimmune, inflammatory disease with obscure etiology. This thesis is based on the hypothesis, that there is a link between respiratory exposures and the development of RA. READ MORE

  4. 12. Studies on the role of anti-citrullinated protein antibodies in rheumatoid arthritis

    Author : Aase Eline Haj Hensvold; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Anti-citrullinated protein antibodies (ACPA) are highly specific for rheumatoid arthritis (RA) and present in about two thirds of all patients at diagnosis. They can be detected already before disease onset and have direct pathogenic effect mediated partly through the Fc (fragment crystalizable) portion with attached Fc-glycan structure. READ MORE

  5. 13. Identification and functional analysis of anti-citrullinated protein antibodies in rheumatoid arthritis

    Author : Yibo He; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rheumatoid arthritis (RA) is a complex autoimmune disease and typically manifested by joint inflammation and bone erosion with approximately 0.5% of the global population affected. To date, it is believed that genetic predisposition (e.g. READ MORE

  6. 14. Epigenetics in health and disease : on smoking, multiple sclerosis, and rheumatoid arthritis disease states

    Author : Mikael Ringh; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The main aim of this thesis was to investigate the genome-wide DNA methylation in tissues associated with the immunopathogenesis of two autoimmune diseases, Rheumatoid Arthritis (RA) and Multiple Sclerosis (MS), as well as smoking-associated methylome patterns in the lung. In Study I, we investigated the methylome of two sets of monozygotic twin pairs, representing two phases of anti citrulline protein antibody (ACPA)-positive RA disease development. READ MORE

  7. 15. Polycystic Ovary Syndrome and Pregnancy : Prenatal Exposures and Pregnancy Complications

    Author : Heiddis Valgeirsdóttir; Anna-Karin Wikström; Inger Sundström Poromaa; Theodora Kunovac Kallak; Marie Blomberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Polycystic ovary syndrome; PCOS; pregnancy; epidemiology; prenatal exposures; pregnancy complications; Anti-Müllerian hormone; AMH; preterm birth; stillbirth; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of fertile age. The aetiology of PCOS is not fully understood and might be affected by foetal exposures. Women with PCOS have an increased risk of pregnancy complications, but information on rare severe complications is scarce. READ MORE