Search for dissertations about: "anti-gliadin antibodies"

Found 3 swedish dissertations containing the words anti-gliadin antibodies.

  2. 1. Coeliac disease : Clinical and immunological aspects

    Author : Tony Hansson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Coeliac disease; cytokines; TGF-beta; tissue transglutaminase; IL-4; IFN-gamma; TNF-alpha; ELISPOT; anti-endomysiumantibodies; anti-gliadin antibodies; Onkologi; Oncology; Onkologi; Klinisk immunologi; Clinical Immunology;

    Abstract : A better immunological definition of coeliac disease and highly discriminatory serum markers are needed to identify children with early mucosal lesions and for rapid follow-up and a better knowledge of antigen reactivity and cytokine production will be needed to clarify the pathogenic mechanisms.The numbers of circulating IgAanti-gliadin antibody-producing (IgAAGA SFC) cells were increased in patients with untreated coeliac disease compared to controls and treated coeliac disease patients. READ MORE

  4. 2. Gliadin-Blocking Peptides In vitro assessment of their potential to alleviate celiac disease development

    Author : Karolina Hoffmann; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; high-gliadin affinity blocking peptides; Caco-2 cells; in vitro digestion; tissue transglutaminase; celiac disease; gliadin; α-amylase trypsin inhibitors;

    Abstract : This thesis work aimed to investigate the potential of synthetic peptides as agents to block wheat prolamins (gliadins) that trigger the development of symptoms in celiac disease. The first step of this investigation included selection and synthesis of peptides with high affinity to gliadins and assessment of the potential of these so-called blocking peptides to limit gliadin reactivity in vitro. READ MORE

  5. 3. Serological markers in subclinical and clinical gluten enteropathy

    Author : Ewa Grodzinsky; Claes Hallert; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : An enzyme-linked immunosorbent assay (ELISA) has been developed for the measurement of anti-gliadin antibodies (AGA), thereby providing a practical and cheap assay for use in the diagnosis of coeliac disease (CD). Since gliadin is a common food antigen for most people, a large group of apparently healthy blood donors (n=l866) was analysed, as well as children and adults with symptoms more or less suggesting CD. READ MORE