Search for dissertations about: "anti-rheumatic drugs"

Showing result 1 - 5 of 19 swedish dissertations containing the words anti-rheumatic drugs.

  2. 1. Persistent inflammatory pathways in rheumatoid arthritis despite anti-rheumatic treatment

    Author : Karina Roxana Gheorghe; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The past years have witnessed tremendous progress in the treatment of rheumatoid arthritis, a chronic debilitating autoimmune disease mainly characterized by joint inflammation with progressive tissue destruction and loss of function. This condition affects 0. READ MORE

  4. 2. Studies of the Role of the Gastrointestinal Tract in Children with Juvenile Idiopathic Arthritis (JIA)

    Author : Anders Öman; Lillemor Berntson; Johan Dicksved; Kjell Alving; Pekka Lahdenne; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; juvenile idiopathic arthritis; coeliac disease; point prevalence; gut microbiota; anti-rheumatic drugs; short-chain fatty acids; exclusive enteral nutrition; specific carbohydrate diet;

    Abstract : Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children, but its cause is not fully established. Changes in the intestinal canal and an unfavourable composition of gut bacteria have been suggested as factors that can increase the risk of developing JIA and influence the disease course. READ MORE

  5. 3. Associations Between Rheumatoid Arthritis and Malignant Lymphomas

    Author : Eva Baecklund; Christer Sundström; Anders Ekbom; Roger Hällgren; Tore Kvien; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; rheumatoid arthritis; malignant lymphoma; diffuse large B-cell lymphoma; disease activity; disease modifying anti-rheumatic drug; Epstein-Barr virus; germinal centre-like non-germinal centre-like subtype; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Abstract : Patients with rheumatoid arthritis (RA) are at increased risk of developing malignant lymphoma, although details about this association remain unclear. The aims of this thesis were to investigate risk factors for lymphoma in patients with RA and to characterize these lymphomas regarding subtype, presence of Epstein-Barr virus (EBV), clinical manifestations and prognosis. READ MORE

  6. 4. Studies on the therapeutic modulation of inflammation in the synovial membrane of rheumatoid arthritis

    Author : Petra Neregård; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation of the synovial membrane that can lead to joint deformity and physical disability. Despite recent progress in the therapeutic field of RA, the exact molecular mechanisms responsible for chronic joint inflammation are not yet completely understood. READ MORE

  7. 5. Patient Reported Outcomes and Orthopedic Surgery in Rheumatoid Arthritis

    Author : Korosh Hekmat; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid Arthritis; Orthopaedic Surgery; Patient Reported Outcomes; Outcomes; Epidemiology;

    Abstract : Orthopedic surgery is used effectively in many patients with severe rheumatoid arthritis RA). The aim of modern pharmacologic treatment is to prevent joint destruction and reduce the need for orthopedic surgery. Patient reported outcomes (PROs) are important measures of the burden of RA. READ MORE