Search for dissertations about: "antibacterial activity"

Showing result 1 - 5 of 104 swedish dissertations containing the words antibacterial activity.

  2. 1. Bioactive Compounds in the Chemical Defence of Marine Sponges : Structure-Activity Relationships and Pharmacological Targets

    Author : Erik Hedner; Lars Bohlin; Per R Jonsson; Raffaele Riccio; Uppsala universitet; []
    Keywords : Pharmacognosy; 5-hydroxytryptamine; agelasine; agelasimine; antibacterial; antifouling; barettin; bromobenzisoxazolone barettin; cytotoxic; marine; secondary metabolite; sponge; Farmakognosi; Agelas; Geodia barretti;

    Abstract : Marine invertebrates, in particular sponges, represent a source of a wide range of secondary metabolites, many of which have been attributed various defensive capabilities against environmental stress factors. In this thesis sponge-derived low-molecular peptide-like compounds and associated analogs are investigated for bioactivity and pharmacological targets. READ MORE

  4. 2. Physiological effects of conditioned medium and passage number on Spodoptera frugiperda Sf9 serum free cultures

    Author : Ingrid Svensson; Lena Häggström; Mats Martinelle; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; Spodoptera frugiperda Sf9; insect cell cultures; conditioned medium; cell cycle phase dynamics; proteolytic activity; antibacterial activity; recombinant protein production; Bioteknik; Bioengineering; Bioteknik;

    Abstract : The aim of this study was to better understand the role of conditioned medium (CM) in Spodoptera frugiperda Sf9 insect cell proliferation and recombinant protein production using the baculovirus expression system. CM was found to stimulate cell proliferation. READ MORE

  5. 3. Pilicides and Curlicides : Design, synthesis, and evaluation of novel antibacterial agents targeting bacterial virulence

    Author : Erik Chorell; Fredrik Almqvist; Stephen Hanessian; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pilicide; curlicide; anti-virulence; chaperone usher pathway; antibacterial; pili; curli; Escherichia coli; biofilm inhibitor; 2-pyridone; peptidomimetic; Organic chemistry; Organisk kemi; Bioorganic chemistry; Bioorganisk kemi; Pharmaceutical chemistry; Läkemedelskemi; Organic synthesis; Organisk syntes; Infectious diseases; Infektionssjukdomar; Biorganic Chemistry; bioorganisk kemi; Infectious Diseases; infektionssjukdomar; datorlingvistik; computational linguistics; organisk kemi; Organic Chemistry;

    Abstract : New strategies are needed to counter the growing problem of bacterial resistance to antibiotics. One such strategy is to design compounds that target bacterial virulence, which could work separately or in concert with conventional bacteriostatic or bactericidal antibiotics. READ MORE

  6. 4. Antibacterial elastomeric materials for biomedical applications

    Author : Annija Stepulane; Chalmers tekniska högskola; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; hydrogels; antibacterial coating; polydimethylsiloxane; elastomer blends; drug-delivery; antimicrobial peptides;

    Abstract : An ageing population in combination with scientific and clinical advancements have led to a steady increase in the use of medical devices. Elastomeric biomaterials – materials displaying rubber-like mechanics – have found widespread applicability in the production of both short- and long-term medical devices. READ MORE

  7. 5. Structural and Antibacterial Properties of Silver(I) Compounds with N-donor Ligands: A Challenge for Medical Applications

    Author : Al-Shimaà A A Massoud; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; X-ray diffraction; silver I compounds; solution chemistry; antibacterial activity;

    Abstract : In this thesis, new silver(I) nitrate compounds with N-donor heterocyclic ligands are described. The structures of the obtained crystalline compounds 1-19 were analysed using X-ray single-crystal diffraction. READ MORE