Search for dissertations about: "antibacterial therapy"

Showing result 1 - 5 of 21 swedish dissertations containing the words antibacterial therapy.

  2. 1. Studies of chronic ulcers and larval therapy

    Author : Helene Wolff; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic ulcers; wounds; larval therapy maggot; MRSA; debriding; proteases; larval therapy; maggot; debriding. proteases;

    Abstract : Our aims in this study were to learn more about chronic ulcer pathogenesis (Paper I) and larval therapy (Paper II-V).Materials and methods: Paper I: 26 bacterial isolates of P. aeruginosa from chronic ulcers were examined by PCR technique for detection of the genes of two virulence factors (elastase and alkaline proteinase). READ MORE

  4. 2. Synthesis of substituted Ring-Fused 2-Pyridones and applications in chemical biology

    Author : Christoffer Bengtsson; Fredrik Almqvist; Paul Helquist; Umeå universitet; []
    Keywords : Synthesis; 2-pyridone; 2-thiazoline; cross coupling; pili; curli; antibacterial; organisk kemi; Organic Chemistry;

    Abstract : Antibiotics have been extensively used to treat bacterial infections since Alexander Fleming’s discovery of penicillin 1928. Disease causing microbes that have become resistant to antibiotic drug therapy are an increasing public health problem. READ MORE

  5. 3. Antibacterial surface coatings for biomedical applications

    Author : Saba Atefyekta; Chalmers tekniska högskola; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Antimicrobial surfaces; mesoporous titania; elastin-like polypeptide; antimicrobial peptide; antibiotic delivery;

    Abstract : Over the past decades there has been a significant increase in the diversity and function of biomaterials. Today, medical practices utilize a large number of biomaterials in the form of medical devices and implants. However, one major obstacle that limits the efficiency of biomaterials is their susceptibility to develop infection. READ MORE

  6. 4. Pharmacometric Models for Antibacterial Agents to Improve Dosing Strategies

    Author : Elisabet I Nielsen; Lena E Friberg; Otto Cars; Mats O Karlsson; Marie Sandström; Alan Forrest; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometrics; pharmacokinetics; pharmacodynamics; modeling; NONMEM; antibiotics; in vitro; time-kill curve; PK PD indices; gentamicin; aminoglycosides; newborn infants; premature infants; cystatin C; Biopharmacy; Biofarmaci; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Abstract : Antibiotics are among the most commonly prescribed drugs. Although the majority of these drugs were developed several decades ago, optimal dosage (dose, dosing interval and treatment duration) have still not been well defined. READ MORE

  7. 5. Hybrid antibacterial microneedle patches against skin infections

    Author : Jill Ziesmer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Skin and soft tissue infections (SSTIs) are a major healthcare burden that has increased in incidence since the beginning of the 21st century resulting in an annual spending of approximately 15 b$ in 2012 in the United States (US).1 Treatment of SSTIs is complex and typically involves the administration of antibiotics. READ MORE