Search for dissertations about: "antibiotic peptide"

Showing result 1 - 5 of 35 swedish dissertations containing the words antibiotic peptide.

2. 1. Antibacterial surface coatings for biomedical applications

   Author : Saba Atefyekta; Chalmers tekniska högskola; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Antimicrobial surfaces; mesoporous titania; elastin-like polypeptide; antimicrobial peptide; antibiotic delivery;

   Abstract : Over the past decades there has been a significant increase in the diversity and function of biomaterials. Today, medical practices utilize a large number of biomaterials in the form of medical devices and implants. However, one major obstacle that limits the efficiency of biomaterials is their susceptibility to develop infection. READ MORE

4. 2. Plantaricins as a novel group of antibacterial compounds and enhancers of antibiotics

   Author : Amani Musa; Hazem Khalaf; Torbjörn Bengtsson; Elena Vikström; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bacteriocin; antimicrobial peptide; plantaricin; antibiotic resistance; PLNC8 αβ; ESKAPE pathogens;

   Abstract : Antibiotics have revolutionized medicine, however, the rapid development of an-tibiotic resistance among bacteria is diminishing their efficacy. Antimicrobial pep-tides produced by Lactobacillus plantarum, i.e., plantaricins, are considered prom-ising alternatives to antibiotics against infections. READ MORE

5. 3. Mechanisms of Adaptation to Deformylase Inhibitors

   Author : Anna Zorzet; Dan Andersson; Paul Rainey; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibiotic resistance; compensatory evolution; compensatory mutations; protein synthesis; initiation factor 2; initiator tRNA; formylation; peptide deformylase inhibitors; Bacteriology; Bakteriologi; Mikrobiologi; Microbiology; Biokemi; Biochemistry; Geography; Geografi;

   Abstract : Antibiotic resistance is a growing problem on a global scale. Increasing numbers of bacteria resistant toward one or multiple antibiotics could return us to the high mortality rates for infectious diseases of the pre-antibiotic era. READ MORE

6. 4. Antimicrobial peptide therapy for tuberculosis infections

   Author : Komal Umashankar Rao; Medicinsk mikrobiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tuberculosis; antimicrobial peptides; mode of action; nanoparticles; novel therapy; membrane active peptides;

   Abstract : Tuberculosis is a communicable disease that persists as a second leading cause for death, by an infectious agent. Several reasons contribute to this issue to this, of which an upsurge in antibiotic resistance is of top concern. Resistance patterns in the form of mono or multidrug resistance was reported to most clinical therapies at our disposal. READ MORE

7. 5. Disarming bacteria : a structure-based approach to design an anti-virulence drug against Listeria monocytogenes

   Author : Melanie Oelker; A. Elisabeth Sauer-Eriksson; Fredrik Almqvist; Karina Persson; Tiziano Tuccinardi; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; antibiotic resistances; anti-virulence drug; Listeria monocytogenes; virulence regulation; PrfA; structure-based drug design; ring-fused 2-pyridones; allosteric regulation; Biochemistry; biokemi; medicinal chemistry; läkemedelskemi; molekylär cellbiologi; molecular cell biology; medicinsk biokemi; Medical Biochemistry; molekylärbiologi; Molecular Biology;

   Abstract : Antibiotic resistances are one of the biggest threats to global health and if we don’t change our behavior and way of using antibiotics we will end up in a ‘post-antibiotic era’, in which common infections and minor injuries can once kill again and up to 10 million deaths per year may occur by 2050. Therefore, there is a high need for new anti-bacterial drugs, especially of alternatives to existing antibiotics with already described resistances. READ MORE