Search for dissertations about: "antibiotic research"

Showing result 1 - 5 of 133 swedish dissertations containing the words antibiotic research.

2. 1. Cracks in the Ivory Tower : Antibiotics Research and the Changes in Academia 1980-2015

   Author : Carl Björvang; Alexandra Waluszewski; Lars Fälting; Oili-Helena Ylijoki; Uppsala universitet; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; antibiotic research; academic capitalism; scientific discoveries; research policy; Swedish research; antibiotic resistance; antibacterial treatment; Ekonomisk historia; Economic History;

   Abstract : At the same time as resistance to antibiotics became an increasingly problematic health care concern around the world, major changes occurred in the condition scientists faced when conducting university-based research. This thesis aims to study these changes as they applied to antibacterial and bacteriological research, and how they influenced the researchers’ ability to make new scientific discoveries. READ MORE

4. 2. New antibiotic resistance genes and their diversity

   Author : Fanny Berglund; Chalmers tekniska högskola; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; metagenomics; β-lactamases; hidden Markov model; antibiotic resistance; carbapenemases; big data; tetracycline resistance;

   Abstract : Antibiotic resistance is increasing worldwide and is considered a severe threat to public health. Often, antibiotic resistance is caused by antibiotic resistance genes, of which many are hypothesized to have been transferred into human pathogens from environmental bacteria. READ MORE

5. 3. Antibiotic resistance gone wild : A One Health perspective on carriage, selection and transmission of Extended-Spectrum Cephalosporinase- and Carbapenemase-producing Enterobacteriaceae

   Author : Clara Atterby; Josef D. Järhult; Nicola Williams; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibiotic resistance; E. coli; K. pneumoniae; ESBL; AmpC; Carbapenemase; ciprofloxacin resistance; colistin resistance; rural; wildlife; birds; sub-MIC; MSC; Cambodia; environment; epidemiology; Infektionssjukdomar; Infectious Diseases;

   Abstract : Antibiotics have saved millions of lives since they came into clinical use during the Second World War in the 1940s. Today, our effective use of antibiotics is under great threat due to emerging antibiotic resistance in bacteria. This thesis addresses the problems of antibiotic resistance from a ”One Health” perspective. READ MORE

6. 4. Computational discovery of antibiotic resistance genes and their horizontal transfer

   Author : David Lund; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; phylogenetic analysis; Antibiotic resistance; horizontal gene transfer; computational screening;

   Abstract : Antibiotic resistance is increasing among clinical infections and represents one of the most serious threats to public health. Pathogens often become resistant by acquiring mobile antibiotic resistance genes (ARGs) via horizontal gene transfer (HGT). READ MORE

7. 5. Composing Policy Interventions for Antibiotic Development

   Author : Christopher Okhravi; Steve McKeever; Francesco Ciabuschi; Enrico Baraldi; Jonathan Michie; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; evidence-based policy; simulation; antibiotics; ontology; composition; alignment; docking; contracts; REA; research and development; design science research; domain-specific language; Information Systems; Informationssystem;

   Abstract : Antibiotic resistance is eroding the efficacy of the drugs we have and, unless future science dictates otherwise, bacteria will eventually become resistant to whatever new antibiotics we discover. We must therefore plan for a continuous stream of innovation. Unfortunately, pharmaceutical firms have left the scene to pursue more profitable areas. READ MORE