Search for dissertations about: "antibiotic tolerance"
Showing result 11 - 15 of 17 swedish dissertations containing the words antibiotic tolerance.
-
11. Physiologically Based Pharmacometric Models for Colistin and the Immune Response to Bacterial Infection
Abstract : Antibiotic treatment failure might be due to bacterial resistance or suboptimal exposure at target site and there is a lack of knowledge on the interaction between antimicrobial pharmacodynamics (PD) and the immune response to bacterial infections. Therefore, it is crucial to develop tools to increase the understanding of drug disposition to better evaluate antibiotic candidates in drug development and to elucidate the role of the immune system in bacterial infections. READ MORE
-
12. Use of rhizobacteria for the alleviation of plant stress
Abstract : Plant growth promoting rhizobacteria are beneficial microbes able to induce plant stress tolerance and antagonise plant pathogens. The present study showed that wheat seedlings pre-treated with Bacillus thuringiensis AZP2 had better tolerance to severe drought stress and showed 78% greater plant biomass and five-fold higher survivorship compared to wheat seedlings not treated with the bacterium. READ MORE
-
13. Evaluation of potential antidiabetic and antibacterial activities of Bolivian nutraceutical plants
Abstract : Type 2 diabetes mellitus is a health problem worldwide that requires the search for novel therapeutic strategies. Natural products are a source of potential therapies due to their acceptation and traditional use or consumption. READ MORE
-
14. Novel tools for the study and diagnosis of bacterial infections : exploring the intersection of microbiology and microfabrication
Abstract : The alarming increase in antibiotic resistance calls for new approaches to study and diagnose bacterial infections. In my thesis, I worked at the intersection of microbiology, microfabrication, and optical probes to develop novel diagnostic and screening assays for microbiology and elucidate bacterial pathogenesis in urinary tract infections (UTI). READ MORE
-
15. FtsH protease and ClpG disaggregase confer fitness advantages to the worldwide prevalent Pseudomonas aeruginosa clone C
Abstract : Pseudomonas aeruginosa is an environmental bacterium and a frequent nosocomial pathogen causing a wide range of opportunistic infections, especially in immunocompromised patients. Clone C is one of the most prevalent groups of closely related strains distributed worldwide in the environment, such as in natural aquatic habitats, and the clinical settings, such as in patients with an underlying functional impairment of the cystic fibrosis transmembrane conductance regulator. READ MORE