Search for dissertations about: "antibiotics and cancer"

Showing result 1 - 5 of 33 swedish dissertations containing the words antibiotics and cancer.

2. 1. Antibiotics use in relation to colorectal cancer risk, survival and postoperative complications

   Author : Sai San Moon Lu; Bethany van Guelpen; Sophia Harlid; Jonas Ludvigsson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; antibiotics; gut microbiome; dysbiosis; cancer-specific survival; surgical site infections; anastomotic leakage; register-based epidemiology; Cancer Epidemiology; cancerepidemiologi; Cancer Epidemiology; cancerepidemiologi; Oncology; onkologi; Surgery; kirurgi;

   Abstract : Background: Growing evidence suggests that antibiotic-induced dysbiosis of gut microbiota potentially contributes to colorectal cancer development and oncological outcomes. However, the role of antibiotics in colorectal cancer incidence, survival and postoperative outcomes at a population level remains incompletely understood. READ MORE

4. 2. Colorectal cancer : Aspects of staging, treatment, recurrence and survival

   Author : Åsa Collin; Joakim Folkesson; Wilhelm Graf; Malin Enblad; Marie-Louise Lydrup; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; recurrence; survival; staging; postoperative complications; Kirurgi; Surgery; Oncology; Onkologi;

   Abstract : Colorectal cancer is the third most common malignancy in the world, and major breakthroughs have been made regarding both surgical and oncological treatment. Still, postoperative complications, such as perineal infections after abdominoperineal resection (APR), are a major cause of morbidity, and distant recurrence rate is nearly 20%. READ MORE

5. 3. RNA modifications and post-transcriptional control in cancer and stem cells

   Author : Giulia Beneventi; Avdelningen för molekylär hematologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA modifications; Pseudouridine; 2’-O-methylation; Splicing; Translation; non-coding RNAs; Cancer; Stem cells; Differentiation; Stress response;

   Abstract : Splicing and translation are two of the key steps of post-transcriptional regulation of gene expression. Their tight regulation is essential for development, whereas their deregulation is involved in cancer pathogenesis. Nevertheless, many of the molecular mechanisms controlling these processes are still unknown. READ MORE

6. 4. Antibiotics in patients on chemotherapy; aspects on pharmacokinetic and pharmacodynamic interactions with antineoplastic drugs

   Author : Anna Nyhlén; Sektion III; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibiotics; neutropenic; antineoplastic agents; pharmacokinetics; pharmacodynamics; PAE; interactions; synergy; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; mykologi; virologi;

   Abstract : The aims of these studies were to investigate the pharmacokinetics of two beta-lactam antibiotics in patients with fever and cytostatic-induced neutropenia and the influence of cytostatic-induced gastrointestinal damage on the absorption of co-trimoxazole. Furthermore to study the pharmacodynamic interactions between antibiotics and antineoplastic drugs and the impact of antineoplastic drugs on the intestinal microflora. READ MORE

7. 5. Markets, Interventions and Externalities : Four Essays in Applied Economics

   Author : Sara Fogelberg Lövgren; Mårten Palme; Mikael Priks; Helena Svaleryd; Stockholms universitet; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Economics; nationalekonomi;

   Abstract : This Ph.D. thesis contains four independent essays summarized as follows. Effects of Competition between Healthcare Providers on Prescription of AntibioticsThe introduction of antibiotics as a medical treatment after World War II helped to dramatically increase life expectancy in the industrialized world. READ MORE