Search for dissertations about: "antibody"
Showing result 11 - 15 of 1320 swedish dissertations containing the word antibody.
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11. Targeted Therapy of Colorectal Cancer : Preclinical Evaluation of a Radiolabelled Antibody
Abstract : Targeted radiotherapy (TRT) of cancer is a promising approach that enables selective treatment of tumour cells, while sparing normal tissue. The humanized monoclonal antibody A33 (huA33) is a potential targeting agent for TRT of colorectal cancer, since its antigen is expressed in more than 95 % of all colorectal carcinomas. READ MORE
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12. Selection and design in antibody phage display
Abstract : The immune system is an important part of the physiology of higher organisms. In the immune system antibodies play a key role in neutralizing and clearing potentially lethal threats from the environment. The importance of antibodies in the immune system has made them come to the attention as a tool in chemistry and medicine. READ MORE
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13. Selection of antigens for antibody-based proteomics
Abstract : The human genome is predicted to contain ~20,500 protein-coding genes. The encoded proteins are the key players in the body, but the functions and localizations of most proteins are still unknown. READ MORE
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14. Antibodies and Antibody Mimics in Binding Assays
Abstract : This thesis presents development of new analytical methods using antibodies and molecularly imprinted polymers (MIPs) in binding assays: 1) The high specificity of antibodies and the wide variety of efficient labels make immunoassay one of the most popular analytical techniques today. Enzyme-linked immunosorbent assay (ELISA) is most widely used, since the enzyme label can be used as a catalyst to provide very high signal amplification. READ MORE
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15. Antibody Feedback Regulation : From Epitope Masking to T Helper Cell Activation
Abstract : Antibodies have the ability to influence the antibody response against the very antigen they are specific for, in a process called antibody feedback regulation. Depending on the nature of the antigen, the antibody response can be either enhanced or almost completely inhibited. READ MORE