Search for dissertations about: "antidepressants"

Showing result 11 - 15 of 121 swedish dissertations containing the word antidepressants.

  2. 11. On the efficacy and prescription of serotonin reuptake inhibitors

    Author : Alexander Lisinski; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antidepressants; antidepressive agents; major depressive disorder; selective serotonin reuptake inhibitor; serotonin and noradrenaline reuptake inhibitor; tricyclic antidepressant;

    Abstract : This thesis addresses several controversial issues regarding commonly used antidepressants, including selective serotonin reuptake inhibitors (SSRIs), serotonin and noradrenaline reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs). To this end, patient-level data from 28 placebo-controlled trials on SSRIs and 13 corresponding trials on the SNRI duloxetine, were requested and obtained. READ MORE

  4. 12. Antidepressant drug effects in vivo: Focus on pharmacokinetic and pharmacodynamic responses in different experimental paradigms

    Author : Cecilia Wikell; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; portacaval shunt; pharmacokinetics; pharmacodynamics; hepatic encephalopathy; enantiomers; drug safety; drug disposition; citalopram; antidepressants; brain microdialysis; behaviour; venlafaxine; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Abstract : Pharmacokinetic and pharmacodynamic activities of the antidepressants venlafaxine (VEN) and citalopram (CIT) were investigated in the portacaval shunted (PCS) rat, a model of chronic hepatic encephalopathy (HE), and normal/control rats. The levels of VEN in serum and brain were higher in PCS rats than in controls after a single injection and chronic treatment with VEN (10 mg/kg). READ MORE

  5. 13. Suicide in Severe Depression: A Longitudinal Case-Control Study

    Author : Louise Brådvik; Lund Psykiatri; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sex differences; Antidepressants; ECT; Suicidal behaviour; Risk factors; Mortality; Depression.; Psychiatry; clinical psychology; psychosomatics; Psykiatri; klinisk psykologi; psykosomatik;

    Abstract : Suicide in Severe Depression. A Longitudinal Case-Control Study. The present thesis is based on a case-control study of suicide victims with a severe depression/ melancholia. READ MORE

  6. 14. Suicide and drugs. Drug related suicide mortality and physicians' prescription patterns

    Author : Anders Carlsten; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Suicide; drug use; drug poisoning; antidepressants; benzodiazepines; prevention.;

    Abstract : Aim: The aims of the study were to 1) analyse a possible association between changes in drug sales and the occurrence of drug poisoning suicides 2) assess the role of benzodiazepines in elderly suicides 3) analyse changes in suicide mortality after the introduction of the selective serotonin reuptake inhibitors, SSRIs 4) examine physicians' inclination to prescribe benzodiazepines in low and high prescribing areas. Method: Information on suicide mortality and death certificates were obtained from Statistics Sweden. READ MORE

  7. 15. A Pill for the Ill? : Depression, Medicalization and Public Health

    Author : Andreas Vilhelmsson; Socialmedicin och global hälsa; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Pharmaceuticalization; Medicalization; Adverse drug reaction; Antidepressants; Consumer reporting; Depression; Medical encounter; Mental health; Public health;

    Abstract : Mental disorders, especially depression, have been increasingly described as a growing burden to global public health. Critics argue, however, that the use of mental health surveys, underlying these descriptions, tends to overestimate the prevalence of mental disorders by not distinguishing everyday experiences of distress from pathological conditions. READ MORE