Search for dissertations about: "antiepileptic drugs and pregnancy"

Showing result 1 - 5 of 9 swedish dissertations containing the words antiepileptic drugs and pregnancy.

2. 1. The informational value and usefulness of serum retinoid measurements. Studies on biological variation, including infancy and pregnancy, and influence of fasting, antiepileptic drugs and ethanol

   Author : Maria Berggren Söderlund; Avdelningen för klinisk kemi och farmakologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; vitamin A deficiency; teratogenicity; ethanol; antiepileptic drugs; caloric restriction; infant; pregnant; biological variation; 13-cis retinoic acid; all-trans retinoic acid; Vitamin A; retinol;

   Abstract : The aims of these studies were to evaluate retinoid measurements, more specifically the performance of all-trans and 13-cis retinoic acids methods in clinical experimental settings and to evaluate the informational value of these measurements in relation to S-Retinol. Biological and analytical variations for retinoids were evaluated for healthy subjects. READ MORE

4. 2. Comorbidity and complications in neurological diseases

   Author : Heléne E.K. Sundelin; Jonas F. Ludvigsson; Henrik Larsson; Rodney Scott; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antiepileptic drugs; autism; cerebral palsy; child; Ehlers-Danlos Syndrome; epilepsy; obstetric; pregnancy; traffic accidents;

   Abstract : Background: Neurological diseases are complex and many share etiology as well as comorbidities. Epilepsy, a brain disorder characterized by an enduring predisposition to generate epileptic seizures and autism spectrum disorder (ASD), are considered to be associated, but the connection is still not fully uncovered. READ MORE

5. 3. Common mechanism for teratogenicity of antiepileptic drugs : Drug-induced embryonic arrhythmia and hypoxia-reoxygenation damage

   Author : Faranak Azarbayjani; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Atiepileptik drugs; embryonic heart; arrhythmia; cleft palate; ROS; antioxidants; Ikr; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Toxicology; toxikologi;

   Abstract : The Antiepilptic drugs (AEDs) phenytoin (PHT), carbamazepine (CBZ), phenobarbital (PB), tri- and dimethadione (TMD and DMD) are known teratogens having a common malformation pattern in human and animal studies. This thesis was designed chiefly to test a hypothesis correlating the teratogenicity of these AEDs to episodes of pharmacologically induced embryonic arrhythmia and hypoxia-reoxygenation damage. READ MORE

6. 4. Hormones, Mood and Cognition

   Author : Kristiina Kask; Inger Sundström Poromaa; Torbjörn Bäckström; Britth-Marie Landgren; Uppsala universitet; []
   Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; startle response; prepulse inhibition; premenstrual dysphoric disorder; menstrual cycle; pregnancy; postpartum period; episodic memory; semantic memory; working memory; progesterone; estradiol; allopregnanolone.; Obstetrics and gynaecology; Obstetrik och gynekologi;

   Abstract : Ovarian steroid hormones are neuroactive steroids with widespread actions in the brain, and are thus able to influence mood, behavior and cognition. In this thesis the effects of progesterone withdrawal and the direct effects of the progesterone metabolite allopregnanolone are evaluated. READ MORE

7. 5. Newer antiepileptic drugs in women of child-bearing age : pharmacokinetic studies during pregnancy, breastfeeding, and contraception

   Author : Inger Öhman; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Epilepsy is a common neurological disorder, affecting men and women almost equally. It has been estimated that 0.3 to 0.4% of pregnant women have epilepsy. READ MORE