Search for dissertations about: "antigen-presentation"
Showing result 1 - 5 of 105 swedish dissertations containing the word antigen-presentation.
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1. The quality control of MHC class I antigen presentation
Abstract : Major histocompatibility complex (MHC) class I molecules present antigenic peptides to CD8+ T cells. The peptides are generated by proteasomes in the cytosol, then translocated across the membrane of the endoplasmic reticulum (ER) by the transporter associated with antigen processing (TAP). READ MORE
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2. Antigen presentation by dendritic cells and immunomodulation by cholera toxin B subunit. Implications for vaccine development
Abstract : Antigen presentation by dendritic cells is the first event that takes place upon initiation of an acquired immune response. The inductive events during antigen presentation will essentially govern the orientation and the magnitude of the subsequent immune responses. READ MORE
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3. Tapasin - The star of the show in HLA-I maturation
Abstract : Human leukocyte antigen class I (HLA-I) molecules are present on the cell surface of all nucleated cells. They bind intracellular peptides and present them to the immune system thus providing a readout to cytotoxic T-cells about the status of a cell. READ MORE
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4. Non-polymorphic MHC class II molecules in antigen presentation
Abstract : .... READ MORE
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5. Dendritic cell presentation of type II collagen
Abstract : Type II collagen (CII) is the main protein component of cartilage and immune recognition of CII plays a critical role for the development of collagen induced arthritis (CIA), a widely used animal model for rheumatoid arthritis (RA). Antigen presentation is an important requirement for the immune response, the more efficient presentation of the antigen the better tolerance will be induced and thereby protect against arthritis. READ MORE